Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | PPARG | P37231 | 5/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 2/20 | 0.49 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | MPC2 | O95563 | 1/20 | 0.43 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4089575 | 0.91 | MAPT (0.50) | MAPTPPARGCA2MAOACISD1 | |
| SCHEMBL8218339 | 0.85 | ALDH1A1 (0.52) | MAPTPPARGCA2MAOACISD1 | |
| SCHEMBL8687818 | 0.84 | MAPT (0.44) | MAPTPPARGCA2MAOACISD1 | |
| SCHEMBL13846717 | 0.81 | CA2 (0.47) | MAPTPPARGCA2MAOACISD1 | |
| SCHEMBL8228771 | 0.81 | CA2 (0.63) | MAPTPPARGCA2MAOACISD1 | |
| SCHEMBL8172885 | 0.81 | AKT1 (0.53) | MAPTPPARGCA2MAOACISD1 | |
| SCHEMBL8685380 | 0.80 | CA2 (0.43) | MAPTPPARGCA2MAOACISD1 | |
| SCHEMBL9570555 | 0.79 | CA2 (0.48) | MAPTPPARGCA2FFAR1PPARA | |
| SCHEMBL8932687 | 0.79 | IDO1 (0.54) | MAPTPPARGALDH1A1KDM4ELMNA | |
| SCHEMBL13846806 | 0.78 | CA2 (0.47) | MAPTPPARGCA2KCNH2FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533933-A1 | BISHETEROCYCLIC COMPOUND | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1993-03-31 | — | — | EP | disclosed |