SCHEMBL868550

SCHEMBL868550

CCc1ccc(C(C)O)nc1

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
ESR1 P03372 5/20 0.44
ESR2 Q92731 5/20 0.44
PPARG P37231 2/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
HRH3 Q9Y5N1 1/20 0.38
CYP1A2 P05177 1/20 0.37
CYP2D6 P10635 1/20 0.37
TRPA1 O75762 1/20 0.34
LPL P06858 1/20 0.34
LIPG Q9Y5X9 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL868276 0.86 PPARG (0.44) KDM4EL3MBTL1ESR1ESR2PPARG
SCHEMBL5513086 0.85 KDM4E (0.43) KDM4EL3MBTL1ESR1ESR2PPARG
SCHEMBL27515092 0.84 KDM4E (0.43) KDM4EL3MBTL1ESR1ESR2PPARG
SCHEMBL23396073 0.82 KDM4E (0.41) KDM4EL3MBTL1ESR1ESR2PPARG
SCHEMBL14406088 0.82 ESR1 (0.47) ESR1ESR2
SCHEMBL23570309 0.82 KDM4E (0.41) KDM4EL3MBTL1ESR1ESR2PPARG
SCHEMBL867987 0.81 PPARG (0.43) KDM4EL3MBTL1ESR1ESR2PPARG
SCHEMBL27668663 0.81 NPC1 (0.44) KDM4EL3MBTL1ESR1ESR2PPARG
SCHEMBL27915396 0.80 ESR1 (0.42) ESR1ESR2PPARG
SCHEMBL14116463 0.79 KDM4E (0.42) KDM4EL3MBTL1ESR1ESR2PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119798143-A Synthesis method of 5-ethyl-2-pyridine ethanol 安徽尖峰北卡药业有限公司 2025-04-11 CN claimed
CN-114031548-A Preparation method of pioglitazone related substance D and related substance D 湖南增达生物科技有限公司 2022-02-11 CN claimed
CN-112978890-A Oilfield sewage flocculant and preparation method thereof 西安威弗莱环境控制技术有限责任公司 2021-06-18 CN claimed
CN-119798143-B Synthesis method of 5-ethyl-2-pyridine ethanol 安徽尖峰北卡药业有限公司 2025-09-30 CN disclosed
CN-119798143-B Synthesis method of 5-ethyl-2-pyridine ethanol 安徽尖峰北卡药业有限公司 2025-09-30 CN disclosed
CN-119798143-A Synthesis method of 5-ethyl-2-pyridine ethanol 安徽尖峰北卡药业有限公司 2025-04-11 CN disclosed
CN-119798143-A Synthesis method of 5-ethyl-2-pyridine ethanol 安徽尖峰北卡药业有限公司 2025-04-11 CN disclosed
CN-119798143-A Synthesis method of 5-ethyl-2-pyridine ethanol 安徽尖峰北卡药业有限公司 2025-04-11 CN disclosed
US-11844776-B2 Composition for treatment and/or prevention of peripheral nerve disorder OSAKA CITY UNIVERSITY (JP) 2023-12-19 US disclosed
EP-3466421-B1 COMPOSITION FOR THE TREATMENT OF PERIPHERAL NERVE DISORDERS UNIV OSAKA CITY (JP) 2022-11-30 EP disclosed
CN-114031548-A Preparation method of pioglitazone related substance D and related substance D 湖南增达生物科技有限公司 2022-02-11 CN disclosed
US-RE36575-E Pyridine and thiazolidinedione derivatives TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2000-02-15 US disclosed
US-5554758-A Method for producing ethers TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1996-09-10 US disclosed
EP-0506273-B1 Method for producing ethers TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1995-05-31 EP disclosed
EP-0506273-A2 Method for producing ethers TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1992-09-30 EP disclosed
EP-0257781-B1 A METHOD FOR PRODUCING THIAZOLIDINEDIONE DERIVATIVES Takeda Chemical Industries, Ltd. (JP) 1991-09-18 EP disclosed
US-4898947-A Pyridine and thiazolidinedione derivatives TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1990-02-06 US disclosed
US-4812570-A Method for producing thiazolidinedione derivatives TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1989-03-14 US disclosed
EP-0257781-A1 A method for producing thiazolidinedione derivatives Takeda Chemical Industries, Ltd. (JP) 1988-03-02 EP disclosed
US-4006127-A Cationic diazacyanine dyestuffs BAYER AKTIENGESELLSCHAFT (DT) 1977-02-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11844776-B2 Composition for treatment and/or prevention of peripheral nerve disorder PMP22, PRPH, NGF KDM4E 3084/4885L3MBTL1 1188/4885ESR1 3450/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.