Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.53 |
| ▸ | DRD3 | P35462 | 2/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | PRNP | P04156 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8685708 | 1.00 | DRD2 (0.53) | DRD2DRD3SIGMAR1ALDH1A1KMT2A | |
| SCHEMBL8687561 | 0.91 | DRD2 (0.53) | DRD2DRD3SIGMAR1ALDH1A1KMT2A | |
| SCHEMBL8687558 | 0.91 | DRD2 (0.53) | DRD2DRD3SIGMAR1ALDH1A1KMT2A | |
| SCHEMBL8314205 | 0.91 | DRD2 (0.55) | DRD2DRD3SIGMAR1ALDH1A1KMT2A | |
| SCHEMBL8314202 | 0.91 | DRD2 (0.55) | DRD2DRD3SIGMAR1ALDH1A1KMT2A | |
| SCHEMBL8685136 | 0.90 | S1PR1 (0.47) | DRD2DRD3SIGMAR1ALDH1A1KMT2A | |
| SCHEMBL8685134 | 0.90 | S1PR1 (0.47) | DRD2DRD3SIGMAR1ALDH1A1KMT2A | |
| SCHEMBL8687919 | 0.89 | DRD2 (0.52) | DRD2DRD3SIGMAR1ALDH1A1POLB | |
| SCHEMBL8687918 | 0.89 | DRD2 (0.52) | DRD2DRD3SIGMAR1ALDH1A1POLB | |
| SCHEMBL8686279 | 0.89 | MEN1 (0.52) | DRD2DRD3SIGMAR1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5723484-A | Benzopyran compounds as 5-HT2C receptor antagonists | ADIR ET COMPAGNIE (FR) | 1998-03-03 | — | — | US | disclosed |
| US-5663191-A | PSYCHIATRIC DISEASES, ANXIETY AND ANTIDEPRESSANTS | ADIR ET COMPAGNIE (FR) | 1997-09-02 | — | — | US | disclosed |