SCHEMBL8685807

SCHEMBL8685807

CCCCCCCCCCCCCCCNCC(C)O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.52
TSHR P16473 1/20 0.52
ANPEP P15144 1/20 0.52
ERAP2 Q6P179 1/20 0.52
EPHX1 P07099 8/20 0.46
S1PR2 O95136 5/20 0.44
S1PR4 O95977 5/20 0.44
S1PR1 P21453 5/20 0.44
S1PR3 Q99500 5/20 0.44
S1PR5 Q9H228 1/20 0.44
ADH1B P00325 1/20 0.43
ADH1C P00326 1/20 0.43
ADH1A P07327 1/20 0.43
ADH4 P08319 1/20 0.43
ADH7 P40394 1/20 0.43
MEN1 O00255 1/20 0.41
RAB9A P51151 1/20 0.41
KMT2A Q03164 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
PKM P14618 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27575789 1.00 ALDH1A1 (0.52) ALDH1A1TSHRANPEPERAP2EPHX1
SCHEMBL8686086 1.00 ALDH1A1 (0.52) ALDH1A1TSHRANPEPERAP2EPHX1
SCHEMBL9949418 1.00 ALDH1A1 (0.52) ALDH1A1TSHRANPEPERAP2EPHX1
SCHEMBL10398805 1.00 ALDH1A1 (0.52) ALDH1A1TSHRANPEPERAP2EPHX1
SCHEMBL8109480 1.00 ALDH1A1 (0.52) ALDH1A1TSHRANPEPERAP2EPHX1
SCHEMBL4141309 1.00 ALDH1A1 (0.52) ALDH1A1TSHRANPEPERAP2EPHX1
SCHEMBL4286294 1.00 ALDH1A1 (0.52) ALDH1A1TSHRANPEPERAP2EPHX1
SCHEMBL8685954 1.00 ALDH1A1 (0.52) ALDH1A1TSHRANPEPERAP2EPHX1
SCHEMBL21541577 1.00 ALDH1A1 (0.52) ALDH1A1TSHRANPEPERAP2EPHX1
SCHEMBL3854136 1.00 ALDH1A1 (0.52) ALDH1A1TSHRANPEPERAP2EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4529528-A Reacting an alkoxylated amine and a phosphite MOBIL OIL CORPORATION (US) 1985-07-16 US claimed
US-5824626-A Process for preparing trithianes and phosphorus acid and/or thiophosphorus acid derivatives THE LUBRIZOL CORPORATION (US) 1998-10-20 US disclosed
EP-0522133-B1 TRITHIANES AND PHOSPHORUS ACID AND/OR THIOPHOSPHORUS ACID DERIVATIVES LUBRIZOL CORP (US) 1995-08-30 EP disclosed
EP-0612839-A1 Liquid compositions for refrigeration systems containing fatty amines, fatty amides, and reaction products of fatty acylating agents The Lubrizol Corporation (US) 1994-08-31 EP disclosed
US-5194166-A Phosphorous amine lubricant additives THE ELCO CORPORATION (US) 1993-03-16 US disclosed
US-5182037-A PHOSPHORUS- AND/OR NITROGEN-CONTAINING DERIVATIVES OF SULFUR-CONTAINING COMPOUNDS, LUBRICANT, FUEL AND FUNCTIONAL FLUID COMPOSITIONS THE LUBRIZOL CORPORATION (US) 1993-01-26 US disclosed
EP-0522133-A1 TRITHIANES AND PHOSPHORUS ACID AND/OR THIOPHOSPHORUS ACID DERIVATIVES. LUBRIZOL CORP (US) 1993-01-13 EP disclosed
EP-0318511-B1 BORATED AMINE SALTS OF MONOTHIOPHOSPHORIC ACIDS The Lubrizol Corporation (US) 1992-09-23 EP disclosed
WO-1992012225-A1 TRITHIANES AND PHOSPHORUS ACID AND/OR THIOPHOSPHORUS ACID DERIVATIVES THE LUBRIZOL CORPORATION (US) 1992-07-23 WO disclosed
US-5130036-A Friction reducing phosphorous alkoxylated amine lubricants THE ELCO CORPORATION (US) 1992-07-14 US disclosed
EP-0325977-B1 PHOSPHITE AMINE LUBRICANT ADDITIVES THE ELCO CORPORATION (US) 1992-03-25 EP disclosed
EP-0456888-A1 Phosphorous amine lubricant additives THE ELCO CORPORATION (US) 1991-11-21 EP disclosed
US-4992184-A Reaction product of arylsulfonic acid and (diol or amine) phosphite MOBIL OIL CORPORATION (US) 1991-02-12 US disclosed
US-4965002-A Reaction product of alkoxylated amine and organic phosphize ELCO CORPORATION (US) 1990-10-23 US disclosed
EP-0325977-A1 Phosphite amine lubricant additives THE ELCO CORPORATION (US) 1989-08-02 EP disclosed
EP-0309486-A1 PHOSPHOROUS- AND SULFUR-CONTAINING LUBRICANT AND FUNCTIONAL FLUID COMPOSITIONS The Lubrizol Corporation (US) 1989-04-05 EP disclosed
US-4755311-A Borated amine salt of dihydrocarbyl monothiophosphoric acid THE LUBRIZOL CORPORATION (US) 1988-07-05 US disclosed
WO-1987007638-A2 PHOSPHOROUS- AND SULFUR-CONTAINING LUBRICANT AND FUNCTIONAL FLUID COMPOSITIONS THE LUBRIZOL CORPORATION (US) 1987-12-17 WO disclosed
US-4557845-A FRICTION REDUCERS AND FUEL CONSUMPTION REDUCERS MOBIL OIL CORPORATION (US) 1985-12-10 US disclosed
US-4529528-A Reacting an alkoxylated amine and a phosphite MOBIL OIL CORPORATION (US) 1985-07-16 US disclosed