Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CDC25A | P30304 | 1/20 | 0.34 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | XIAP | P98170 | 2/20 | 0.32 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | CCR4 | P51679 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8686109 | 1.00 | ALDH1A1 (0.34) | ALDH1A1MAPTHPGDCDC25AFDFT1 | |
| SCHEMBL8686114 | 1.00 | ALDH1A1 (0.34) | ALDH1A1MAPTHPGDCDC25AFDFT1 | |
| SCHEMBL8684367 | 0.89 | GSK3B (0.36) | ALDH1A1MAPTCDC25AFDFT1POLB | |
| SCHEMBL8684377 | 0.89 | GSK3B (0.36) | ALDH1A1MAPTCDC25AFDFT1POLB | |
| SCHEMBL8684371 | 0.89 | GSK3B (0.36) | ALDH1A1MAPTCDC25AFDFT1POLB | |
| SCHEMBL8636205 | 0.88 | FDFT1 (0.43) | ALDH1A1MAPTFDFT1HTTCCR4 | |
| SCHEMBL8684150 | 0.88 | ALDH1A1 (0.39) | ALDH1A1MAPTCDC25AFDFT1POLB | |
| SCHEMBL8636199 | 0.88 | FDFT1 (0.43) | ALDH1A1MAPTFDFT1HTTCCR4 | |
| SCHEMBL8636201 | 0.88 | FDFT1 (0.43) | ALDH1A1MAPTFDFT1HTTCCR4 | |
| SCHEMBL8684153 | 0.88 | ALDH1A1 (0.39) | ALDH1A1MAPTCDC25AFDFT1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5770594-A | ANTICHOLESTEROL AGENTS, INHIBITORS OF CHOLESTEROL SYNTHESIS | PFIZER INC. (US) | 1998-06-23 | — | — | US | claimed |
| WO-1996020184-A1 | NAPHTHYL-BENZOXAZEPINES OR -BENZOTHIAZEPINES AS SQUALENE SYNTHETASE INHIBITORS | PFIZER INC. (US) | 1996-07-04 | — | — | WO | claimed |
| US-5770594-A | ANTICHOLESTEROL AGENTS, INHIBITORS OF CHOLESTEROL SYNTHESIS | PFIZER INC. (US) | 1998-06-23 | — | — | US | disclosed |
| WO-1996020184-A1 | NAPHTHYL-BENZOXAZEPINES OR -BENZOTHIAZEPINES AS SQUALENE SYNTHETASE INHIBITORS | PFIZER INC. (US) | 1996-07-04 | — | — | WO | disclosed |