Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | FDPS | P14324 | 6/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.33 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL532287 | 0.85 | LPAR3 (0.50) | FDPSLPAR5LPAR3LPAR1LPAR2 | |
| SCHEMBL22783128 | 0.77 | FDPS (0.35) | FDPSLPAR5 | |
| SCHEMBL17233052 | 0.77 | — | — | |
| SCHEMBL27936191 | 0.76 | FFAR4 (0.46) | CYP3A4FDPSLPAR5LPAR3LPAR1 | |
| SCHEMBL8858248 | 0.76 | CYP3A4 (0.50) | CYP3A4FDPSTSHRL3MBTL1ALDH1A1 | |
| Phosphine SCHEMBL27893484 | 0.75 | — | — | |
| SCHEMBL27810796 | 0.75 | TSHR (0.52) | CYP3A4FDPSTSHRL3MBTL1LPAR5 | |
| SCHEMBL29093890 | 0.74 | CYP3A4 (0.65) | CYP3A4TSHRL3MBTL1LPAR3LPAR1 | |
| SCHEMBL22249 | 0.72 | — | — | |
| SCHEMBL29145651 | 0.71 | CYP3A4 (0.50) | CYP3A4TSHRL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998034945-A1 | TARGETED MODIFICATION OF THE CCR-5 GENE | EPOCH PHARMACEUTICALS, INC. (US) | 1998-08-13 | — | — | WO | disclosed |