SCHEMBL8686123

SCHEMBL8686123

CCCCCC(CC)OC(=O)OC1CCC[N]1

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 2/20 0.34
PRKCA P17252 1/20 0.33
PRKCD Q05655 1/20 0.33
NAAA Q02083 2/20 0.33
CTSK P43235 1/20 0.30
PLA2G2C Q5R387 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8683170 0.99 NAAA (0.35) EPHX2PRKCAPRKCDNAAAPLA2G2C
SCHEMBL8680824 0.99 NAAA (0.35) EPHX2PRKCAPRKCDNAAAPLA2G2C
SCHEMBL8681243 0.99 NAAA (0.35) EPHX2PRKCAPRKCDNAAAPLA2G2C
SCHEMBL8681205 0.99 NAAA (0.35) EPHX2PRKCAPRKCDNAAAPLA2G2C
SCHEMBL8683157 0.99 NAAA (0.35) EPHX2PRKCAPRKCDNAAAPLA2G2C
SCHEMBL8681042 0.99 NAAA (0.35) EPHX2PRKCAPRKCDNAAAPLA2G2C
SCHEMBL8683116 0.96 EPHX2 (0.36) EPHX2PRKCAPRKCDNAAACTSK
SCHEMBL8683210 0.95 NAAA (0.37) EPHX2PRKCAPRKCDNAAAPLA2G2C
SCHEMBL8680799 0.95 NAAA (0.37) EPHX2PRKCAPRKCDNAAAPLA2G2C
SCHEMBL8681216 0.95 NAAA (0.37) EPHX2PRKCAPRKCDNAAAPLA2G2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5843983-A Diphenylethane compounds containing a saturated heterocyclic group, their preparation, and their therapeutic use SANKYO COMPANY, LIMITED (JP) 1998-12-01 US disclosed
EP-0790235-A1 Diaryl alkane derivatives containing an alicyclic group, their preparation and their therapeutic and prophylactic uses SANKYO COMPANY LIMITED (JP) 1997-08-20 EP disclosed