Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 9/20 | 0.65 |
| ▸ | HTR1D | P28221 | 7/20 | 0.65 |
| ▸ | HTR1A | P08908 | 2/20 | 0.62 |
| ▸ | HTR6 | P50406 | 7/20 | 0.60 |
| ▸ | NOS3 | P29474 | 2/20 | 0.54 |
| ▸ | NOS1 | P29475 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8686137 | 1.00 | HTR1B (0.65) | HTR1BHTR1DHTR1AHTR6NOS3 | |
| SCHEMBL8979700 | 0.85 | HTR1B (0.68) | HTR1BHTR1DHTR1AHTR6 | |
| SCHEMBL8688634 | 0.82 | HTR1B (0.67) | HTR1BHTR1DHTR1AHTR6NOS3 | |
| SCHEMBL8686525 | 0.82 | HTR1B (0.67) | HTR1BHTR1DHTR1AHTR6NOS3 | |
| SCHEMBL8688640 | 0.82 | HTR1B (0.67) | HTR1BHTR1DHTR1AHTR6NOS3 | |
| SCHEMBL8979694 | 0.80 | HTR1B (0.64) | HTR1BHTR1DHTR1AHTR6 | |
| SCHEMBL8208343 | 0.79 | HTR1B (1.00) | HTR1BHTR1DHTR1AHTR6 | |
| SCHEMBL8208346 | 0.79 | HTR1B (1.00) | HTR1BHTR1DHTR1AHTR6 | |
| SCHEMBL8508432 | 0.79 | HTR1B (1.00) | HTR1BHTR1DHTR1AHTR6 | |
| SCHEMBL8979714 | 0.79 | HTR1B (0.63) | HTR1BHTR1DHTR1AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5770742-A | SEROTONIN RECEPTOR SELECTIVITY, MIGRAINES | ALLELIX BIOPHARMACEUTICALS INC. (CA) | 1998-06-23 | — | — | US | disclosed |
| WO-1997043281-A1 | THIOPHENE- AND FURAN-TRYPTAMINE DERIVATIVES | ALLELIX BIOPHARMACEUTICALS INC. (CA) | 1997-11-20 | — | — | WO | disclosed |