Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 8/20 | 0.68 |
| ▸ | HTR1D | P28221 | 6/20 | 0.68 |
| ▸ | HTR1A | P08908 | 2/20 | 0.64 |
| ▸ | HTR6 | P50406 | 7/20 | 0.62 |
| ▸ | GABRP | O00591 | 3/20 | 0.56 |
| ▸ | GABRD | O14764 | 3/20 | 0.56 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.56 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.56 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.56 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.56 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.56 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.56 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.56 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.56 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.56 |
| ▸ | GABRE | P78334 | 3/20 | 0.56 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.56 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.56 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.56 |
| ▸ | GABRQ | Q9UN88 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8979714 | 0.87 | HTR1B (0.63) | HTR1BHTR1DHTR1AHTR6GABRP | |
| SCHEMBL8686140 | 0.85 | HTR1B (0.65) | HTR1BHTR1DHTR1AHTR6 | |
| SCHEMBL8686137 | 0.85 | HTR1B (0.65) | HTR1BHTR1DHTR1AHTR6 | |
| SCHEMBL8979694 | 0.84 | HTR1B (0.64) | HTR1BHTR1DHTR1AHTR6 | |
| SCHEMBL8979693 | 0.84 | HTR6 (0.65) | HTR1BHTR1DHTR1AHTR6GABRP | |
| SCHEMBL8472864 | 0.84 | HTR1B (0.64) | HTR1BHTR1DHTR1AHTR6GABRP | |
| SCHEMBL8979688 | 0.83 | HTR1B (0.60) | HTR1BHTR1DHTR1AHTR6GABRP | |
| SCHEMBL8686525 | 0.82 | HTR1B (0.67) | HTR1BHTR1DHTR1AHTR6 | |
| SCHEMBL8688634 | 0.82 | HTR1B (0.67) | HTR1BHTR1DHTR1AHTR6 | |
| SCHEMBL8688640 | 0.82 | HTR1B (0.67) | HTR1BHTR1DHTR1AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502065-A | TREATING HEADACHES | PFIZER INC. (US) | 1996-03-26 | — | — | US | disclosed |
| WO-1993021178-A1 | INDOLE DERIVATIVES AS 5-HT1-LIKE AGONISTS | PFIZER LIMITED (GB) | 1993-10-28 | — | — | WO | disclosed |