Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 2/20 | 0.37 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.35 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.35 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.35 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.35 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.35 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.35 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.35 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.35 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.35 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.35 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.35 |
| ▸ | PSMB6 | P28072 | 1/20 | 0.35 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.35 |
| ▸ | PSMB3 | P49720 | 1/20 | 0.35 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.35 |
| ▸ | PSMA6 | P60900 | 1/20 | 0.35 |
| ▸ | PSMA8 | Q8TAA3 | 1/20 | 0.35 |
| ▸ | PSMB7 | Q99436 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7311648 | 0.94 | PSMB5 (0.37) | PSMB5ALDH1A1POLBUSP2MAPT | |
| SCHEMBL7311340 | 0.91 | POLB (0.40) | ALDH1A1POLBUSP2MAPTHSD17B10 | |
| SCHEMBL7311319 | 0.90 | ALDH1A1 (0.37) | ALDH1A1POLBUSP2MAPTHSD17B10 | |
| SCHEMBL7306114 | 0.89 | ALDH1A1 (0.36) | ALDH1A1POLBUSP2MAPTHSD17B10 | |
| SCHEMBL7313603 | 0.89 | ALDH1A1 (0.40) | ALDH1A1POLBUSP2MAPTHSD17B10 | |
| SCHEMBL7310588 | 0.88 | HPGD (0.41) | ALDH1A1POLBUSP2MAPTHSD17B10 | |
| SCHEMBL7310667 | 0.88 | ALDH1A1 (0.39) | ALDH1A1POLBUSP2MAPTHSD17B10 | |
| SCHEMBL7312708 | 0.88 | ALDH1A1 (0.37) | PSMB5ALDH1A1POLBUSP2MAPT | |
| SCHEMBL7306338 | 0.88 | ALDH1A1 (0.38) | ALDH1A1POLBUSP2MAPTHSD17B10 | |
| SCHEMBL7310689 | 0.88 | ALDH1A1 (0.35) | ALDH1A1POLBUSP2MAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5834508-A | PROTEASE ENZYME INHIBITORS; MUSCLE DISORDERS | MITSUBISHI CHEMICAL CORPORATION (JP) | 1998-11-10 | — | — | US | disclosed |
| US-5639783-A | POTENT PROTEASE INHIBITOR FOR TREATING MUSCULAR, NERVOUS SYSTEM DISEASES | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-06-17 | — | — | US | disclosed |