Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.45 |
| ▸ | PPARA | Q07869 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8686238 | 0.77 | PPARG (0.49) | PPARGPPARAKDM4EMEN1RECQL | |
| SCHEMBL8777227 | 0.76 | PDE3B (0.49) | TSHRKDM4EKMT2AMAPT | |
| SCHEMBL8416461 | 0.75 | PPARG (0.51) | PPARGPPARAKDM4E | |
| SCHEMBL8415924 | 0.74 | PPARG (0.44) | PPARGPPARAKDM4E | |
| SCHEMBL27380440 | 0.71 | TAS1R3 (0.44) | TSHRKMT2ATAS1R3TAS1R1MAPT | |
| SCHEMBL27990055 | 0.70 | PDE3B (0.44) | TSHRKDM4EMAPT | |
| SCHEMBL31114370 | 0.70 | POLB (0.44) | PPARATSHRMEN1KMT2ATAS1R3 | |
| SCHEMBL15549044 | 0.69 | KDM4E (0.57) | PPARGPPARAKDM4EMEN1RECQL | |
| SCHEMBL25268149 | 0.69 | F2 (0.40) | PPARGPPARAMEN1KMT2A | |
| SCHEMBL10767353 | 0.69 | AKR1C3 (0.48) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5795914-A | Phenylalkan(en)oic acid | ONO PHARMACEUTICAL CO., LTD. (JP) | 1998-08-18 | — | — | US | disclosed |