Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 11/20 | 0.60 |
| ▸ | RARG | P13631 | 10/20 | 0.60 |
| ▸ | RARA | P10276 | 7/20 | 0.60 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | CRABP2 | P29373 | 1/20 | 0.60 |
| ▸ | RXRA | P19793 | 12/20 | 0.45 |
| ▸ | RXRB | P28702 | 9/20 | 0.44 |
| ▸ | RXRG | P48443 | 6/20 | 0.44 |
| ▸ | CYP26B1 | Q9NR63 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8580705 | 0.83 | RARB (0.65) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL7715323 | 0.82 | RARB (0.80) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL7882967 | 0.81 | RARB (0.68) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL7714910 | 0.78 | RARB (0.58) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL8681621 | 0.78 | RARB (0.55) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL8683606 | 0.78 | RARB (0.51) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL19342932 | 0.77 | RARB (0.68) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL7872264 | 0.76 | RARB (0.62) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL6373022 | 0.76 | RARB (0.75) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL22426598 | 0.76 | RARB (0.67) | RARBRARGRARACYP26A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5716624-A | USEFUL FOR TREATING DERMATOLOGICAL, RHEUMATIC, RESPIRATORY, CARDIOVASCULAR, OPTHALMOLOGICAL DISORDERS, AS WELL AS MAMMALIAN SKIN AND HAIR CONDITIONS/DISORDERS | C.I.R.D. GALDERMA (FR) | 1998-02-10 | — | — | US | claimed |
| US-5716624-A | USEFUL FOR TREATING DERMATOLOGICAL, RHEUMATIC, RESPIRATORY, CARDIOVASCULAR, OPTHALMOLOGICAL DISORDERS, AS WELL AS MAMMALIAN SKIN AND HAIR CONDITIONS/DISORDERS | C.I.R.D. GALDERMA (FR) | 1998-02-10 | — | — | US | disclosed |