Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 13/20 | 0.65 |
| ▸ | RARG | P13631 | 13/20 | 0.65 |
| ▸ | RARA | P10276 | 8/20 | 0.65 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | CRABP2 | P29373 | 1/20 | 0.65 |
| ▸ | RXRA | P19793 | 9/20 | 0.46 |
| ▸ | RXRB | P28702 | 8/20 | 0.45 |
| ▸ | RXRG | P48443 | 6/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8772690 | 0.83 | RARB (0.45) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL27304274 | 0.83 | RARB (0.62) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL8686332 | 0.83 | RARB (0.60) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL19342932 | 0.81 | RARB (0.68) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL8683606 | 0.81 | RARB (0.51) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL22426598 | 0.80 | RARB (0.67) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL19342916 | 0.80 | RARB (0.67) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL8681621 | 0.79 | RARB (0.55) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL8681657 | 0.79 | RXRA (0.51) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL29353973 | 0.79 | RARB (1.00) | RARBRARGRARACYP26A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5798372-A | ADMINISTERING THE RETENOIDS PRIOR, DURING OR AFTER ANGIOPLASTY | ALLERGAN (US) | 1998-08-25 | — | — | US | disclosed |