Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 4/20 | 0.36 |
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9620076 | 0.79 | MAOA (0.38) | POLBCYP3A4TDP1MAOAMAOB | |
| SCHEMBL571851 | 0.79 | CYP3A4 (0.42) | POLBCYP3A4TDP1MAOAMAOB | |
| SCHEMBL28869824 | 0.79 | CYP3A4 (0.42) | POLBCYP3A4TDP1MAOAMAOB | |
| SCHEMBL27459575 | 0.74 | SMN1; SMN2 (0.39) | POLBCYP3A4TDP1MAOAMAOB | |
| SCHEMBL28133852 | 0.73 | CYP3A4 (0.46) | POLBCYP3A4TDP1MAOAMAOB | |
| SCHEMBL28192768 | 0.72 | CYP3A4 (0.37) | POLBCYP3A4TDP1MAOAMAOB | |
| SCHEMBL9503458 | 0.71 | CYP3A4 (0.51) | POLBCYP3A4TDP1MAOAMAOB | |
| SCHEMBL768176 | 0.70 | TDP1 (0.46) | POLBCYP3A4TDP1MAOAMAOB | |
| SCHEMBL19358248 | 0.70 | CYP3A4 (0.46) | POLBCYP3A4TDP1MAOAMAOB | |
| SCHEMBL8098610 | 0.70 | TDP1 (0.46) | POLBCYP3A4TDP1MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719295-A | FROM N-ALKYL NITROPHTHALAMIDE | GENERAL ELECTRIC COMPANY (US) | 1998-02-17 | — | — | US | claimed |
| EP-0684232-A1 | Process for preparing bis(ether anhydrides) | GENERAL ELECTRIC COMPANY (US) | 1995-11-29 | — | — | EP | claimed |