SCHEMBL868763

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL868572	0.93	EIF2AK3 (0.79)	EIF2AK3RIPK1EIF2AK2EIF2AK1NTRK1
	SCHEMBL870100	0.93	EIF2AK3 (0.78)	EIF2AK3RIPK1EIF2AK2EIF2AK1NTRK1
	SCHEMBL27975781	0.93	EIF2AK3 (0.64)	EIF2AK3RIPK1EIF2AK2EIF2AK1NTRK1
	SCHEMBL869430	0.89	EIF2AK3 (0.68)	EIF2AK3RIPK1EIF2AK2EIF2AK1NTRK1
	SCHEMBL24491378	0.88	RIPK1 (0.78)	EIF2AK3RIPK1EIF2AK2EIF2AK1NTRK1
	SCHEMBL29651790	0.88	RIPK1 (0.78)	EIF2AK3RIPK1EIF2AK2EIF2AK1NTRK1
	SCHEMBL868108	0.87	EIF2AK3 (0.69)	EIF2AK3RIPK1EIF2AK2EIF2AK1NTRK1
	SCHEMBL28813551	0.87	EIF2AK3 (0.68)	EIF2AK3RIPK1EIF2AK2EIF2AK1NTRK1
	SCHEMBL2374760	0.87	EIF2AK3 (0.67)	EIF2AK3RIPK1EIF2AK2EIF2AK1NTRK1
	SCHEMBL868503	0.86	EIF2AK3 (1.00)	EIF2AK3RIPK1EIF2AK2EIF2AK1NTRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.