SCHEMBL86878

SCHEMBL86878

C=COC(=O)C1CC(=O)c2cc(Cl)ccc2S1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
VHL P40337 1/20 0.40
ELOC Q15369 1/20 0.40
ELOB Q15370 1/20 0.40
HPGD P15428 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
GSK3B P49841 2/20 0.34
KDM4E B2RXH2 3/20 0.33
NPC1 O15118 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
AR P10275 1/20 0.32
GAA P10253 1/20 0.31
TSHR P16473 1/20 0.31
IDO1 P14902 1/20 0.30
TDO2 P48775 1/20 0.30
TGM2 P21980 1/20 0.30
TUBB4A P04350 1/20 0.30
TUBB P07437 1/20 0.30
TUBA3C P0DPH7 1/20 0.30
TUBA1B P68363 1/20 0.30
TUBA4A P68366 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL86831 0.84 MEN1 (0.41) VHLELOCELOBHPGDL3MBTL1
SCHEMBL13871480 0.82 GSK3B (0.39) HPGDGSK3BKDM4ENPC1
SCHEMBL85980 0.82 VHL (0.35) VHLELOCELOBHPGDL3MBTL1
SCHEMBL85777 0.80 KMT2A (0.40) VHLELOCELOBHPGDKDM4E
SCHEMBL84260 0.80 VHL (0.46) VHLELOCELOBHPGDL3MBTL1
SCHEMBL84470 0.79 VHL (0.33) VHLELOCELOBHPGDL3MBTL1
SCHEMBL87396 0.79 VHL (0.36) VHLELOCELOBHPGDL3MBTL1
SCHEMBL87186 0.78 VHL (0.38) VHLELOCELOBHPGDL3MBTL1
SCHEMBL87130 0.72 VHL (0.37) VHLELOCELOBHPGDL3MBTL1
SCHEMBL67751 0.69 KDM4E (0.54) VHLELOCELOBHPGDL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2053095-B2 Ink composition and inkjet recording method using the same FUJIFILM CORP (JP) 2017-02-22 EP disclosed
EP-2053095-B1 Ink composition and inkjet recording method using the same FUJIFILM CORP (JP) 2014-03-26 EP disclosed
US-8129447-B2 Ink composition and inkjet recording method using the same FUJIFILM CORPORATION (JP) 2012-03-06 US disclosed
US-8129447-B2 Ink composition and inkjet recording method using the same FUJIFILM CORPORATION (JP) 2012-03-06 US disclosed
EP-2053095-A2 Ink composition and inkjet recording method using the same Fujifilm Corporation (JP) 2009-04-29 EP disclosed
US-20090087575-A1 INK COMPOSITION AND INKJET RECORDING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed
US-20090087575-A1 INK COMPOSITION AND INKJET RECORDING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090087575-A1 INK COMPOSITION AND INKJET RECORDING METHOD USING THE SAME RB1, IK, NOX1 VHL 3930/4885ELOC 3228/4885ELOB 895/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.