Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 3/20 | 0.52 |
| ▸ | CDK1 | P06493 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 12/20 | 0.51 |
| ▸ | CA2 | P00918 | 12/20 | 0.51 |
| ▸ | CA9 | Q16790 | 8/20 | 0.51 |
| ▸ | CA12 | O43570 | 8/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | CA4 | P22748 | 2/20 | 0.50 |
| ▸ | CA7 | P43166 | 2/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.48 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.47 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.47 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8691553 | 0.88 | PTPN7 (0.54) | CDK2CDK1CA1CA2CA9 | |
| SCHEMBL8640966 | 0.86 | KMT2A (0.56) | CDK2CDK1CA1CA2CA9 | |
| SCHEMBL8688685 | 0.85 | CDK2 (0.54) | CDK2CDK1CA1CA2CA9 | |
| SCHEMBL8692528 | 0.85 | CDK2 (0.54) | CDK2CDK1CA1CA2CA9 | |
| SCHEMBL8642022 | 0.85 | CDK2 (0.64) | CDK2CDK1CA1CA2CA9 | |
| SCHEMBL8694108 | 0.85 | CDK2 (0.64) | CDK2CDK1CA1CA2CA9 | |
| SCHEMBL8690975 | 0.85 | KMT2A (0.57) | CDK2CDK1CA1CA2CA9 | |
| SCHEMBL8732480 | 0.85 | KMT2A (0.47) | CDK2CDK1CA1CA2CA9 | |
| SCHEMBL8688441 | 0.85 | CDK2 (0.47) | CDK2CDK1CA1CA2CA9 | |
| SCHEMBL8691753 | 0.83 | CDK2 (0.66) | CDK2CDK1CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5760068-A | NONSTEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G.D. SEARLE & CO. (US) | 1998-06-02 | — | — | US | disclosed |
| US-5756529-A | ANTIINFLAMMATORY | G.D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |