SCHEMBL868882

SCHEMBL868882

C#Cc1cn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)[nH]c1=O

nearest known ligand 0.72

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TK1 P04183 3/20 0.70
LMNA P02545 2/20 0.70
SMN1; SMN2 Q16637 2/20 0.70
ALOX12 P18054 1/20 0.66
ADRA1A P35348 1/20 0.66
TK2 O00142 1/20 0.65
CYP1A2 P05177 1/20 0.64
CYP3A4 P08684 1/20 0.64
TSHR P16473 1/20 0.64
BLM P54132 1/20 0.64
PMP22 Q01453 1/20 0.64
NPSR1 Q6W5P4 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1417715 1.00 TK1 (0.70) TK1LMNASMN1; SMN2ALOX12ADRA1A
SCHEMBL29408827 1.00 TK1 (0.70) TK1LMNASMN1; SMN2ALOX12ADRA1A
SCHEMBL8693044 1.00 TK1 (0.70) TK1LMNASMN1; SMN2ALOX12ADRA1A
SCHEMBL6270422 1.00 TK1 (0.70) TK1LMNASMN1; SMN2ALOX12ADRA1A
SCHEMBL18032569 1.00 TK1 (0.70) TK1LMNASMN1; SMN2ALOX12ADRA1A
SCHEMBL18032571 1.00 TK1 (0.70) TK1LMNASMN1; SMN2ALOX12ADRA1A
SCHEMBL14459937 1.00 TK1 (0.70) TK1LMNASMN1; SMN2ALOX12ADRA1A
SCHEMBL15740180 1.00 TK1 (0.70) TK1LMNASMN1; SMN2ALOX12ADRA1A
SCHEMBL18032570 1.00 TK1 (0.70) TK1LMNASMN1; SMN2ALOX12ADRA1A
SCHEMBL6270418 1.00 TK1 (0.70) TK1LMNASMN1; SMN2ALOX12ADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2708 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12612662-B2 DNA repair site detection for personal genomics, epigenomics, and gene therapy SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 2026-04-28 US claimed
US-20260109989-A1 COMPOSITIONS AND METHODS FOR THE SYNTHESIS AND IDENTIFICATION OF COVALENT APTAMERS UNIV HAWAII (US) 2026-04-23 US claimed
US-20260103824-A1 Compositions and Methods for Selectively Synthesizing Triple-indexed cDNA Libraries UNIV ROCKEFELLER (US) 2026-04-16 US claimed
US-20260071273-A1 METHODS FOR NUCLEIC ACID SEQUENCING NANOHYB LLC (US) 2026-03-12 US claimed
US-20260062668-A1 CLICK CHEMISTRY LIGAND UNIV NORTHEASTERN (US) 2026-03-05 US claimed
US-20260034158-A1 METHODS OF TREATING CANCER OF THE CENTRAL NERVOUS SYSTEM COMPRISING 5-ETHYNYL-2'-DEOXYURIDINE UNIV NORTH CAROLINA CHAPEL HILL (US) 2026-02-05 US claimed
EP-4622984-A1 CLICK CHEMISTRY LIGAND Northeastern University (US) 2025-10-01 EP claimed
EP-4623073-A2 METHODS FOR ASSESSING PROLIFERATION POTENCY OF GENE-EDITED T CELLS Iovance Biotherapeutics, Inc. (US) 2025-10-01 EP claimed
US-12371694-B2 Compositions and methods for the synthesis and identification of covalent aptamers UNIVERSITY OF HAWAII (US) 2025-07-29 US claimed
EP-4558641-A1 METHODS FOR DETECTION AND REDUCTION OF SAMPLE PREPARATION-INDUCED METHYLATION ARTIFACTS Guardant Health, Inc. (US) 2025-05-28 EP claimed
WO-2016029889-A1 METHOD OF DETERMINING THE ACTIVITY OF ENZYMES CONVERTING CYTOSINE DERIVATIVES TO URACIL DERIVATIVES IN CELLS, TISSUES AND ORGANISMS UNIVERZITA PALACKEHO V OLOMOUCI (CZ) 2016-03-03 WO claimed
US-20160051690-A1 METHODS FOR THE DEVELOPMENT OF VACCINES BASED ON OLIGOSACCHARIDE-OLIGONUCLEOTIDE CONJUGATES UNIV BRANDEIS (US) 2016-02-25 US claimed
WO-2015086818-A1 OPTICALLY ACTIVATED RECEPTORS IST AUSTRIA (INSTITUTE OF SCIENCE AND TECHNOLOGY AUSTRIA) (AT) 2015-06-18 WO claimed
US-20150057243-A1 Compositions and Methods for the Inhibition of Methyltransferases NORTHERN UNIVERSITY (US) 2015-02-26 US claimed
WO-2013151975-A1 COMPOSITIONS AND METHODS FOR THE INHIBITION OF METHYLTRANSFERASES NORTHEASTERN UNIVERSITY (US) 2013-10-10 WO claimed
US-6864049-B1 Method for producing hybridization complexes whose stability is substantially independent of the base composition of two hybridized nucleic acid molecules APPLIGENE-ONCOR S.A. (FR) 2005-03-08 US claimed
US-5633360-A CONTAINS AT LEAST TWO NUCLEOSIDE RESIDUES AND INTERNUCLEOTIDE LINKAGES GILEAD SCIENCES, INC. (US) 1997-05-27 US claimed
US-5137724-A Active ingredient and potentiating ingredient; cytidine and vridine derivatives STICHTING REGA VZW (BE) 1992-08-11 US claimed
EP-0208550-B1 ANTIVIRAL COMPOUNDS THE WELLCOME FOUNDATION LIMITED (GB) 1991-05-22 EP claimed
EP-0208550-A2 Antiviral compounds THE WELLCOME FOUNDATION LIMITED (GB) 1987-01-14 EP claimed