Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CDC25B | P30305 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | POLB | P06746 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28764296 | 0.79 | TP53 (0.52) | CYP2D6CYP2C9KDM4EALDH1A1POLB | |
| SCHEMBL1162404 | 0.79 | CDC25B (0.80) | CYP2D6CYP2C9CDC25BKDM4EALDH1A1 | |
| SCHEMBL222908 | 0.78 | NR4A1 (0.60) | CDC25BKDM4EALDH1A1POLBHPGD | |
| SCHEMBL7030453 | 0.78 | HIF1A (0.51) | CYP2D6CYP2C9KDM4EALDH1A1POLB | |
| SCHEMBL7099574 | 0.77 | NPC1 (0.56) | KDM4EALDH1A1POLBHPGDHSD17B10 | |
| SCHEMBL10889935 | 0.77 | CDC25B (0.78) | CYP2D6CYP2C9CDC25BKDM4EALDH1A1 | |
| SCHEMBL17423273 | 0.77 | NQO1 (0.52) | KDM4EALDH1A1POLBHPGDHSD17B10 | |
| Acridine SCHEMBL31147690 | 0.77 | NR4A1 (0.58) | CDC25BKDM4EALDH1A1POLBHPGD | |
| Water SCHEMBL7769203 | 0.77 | NR4A1 (0.58) | CDC25BKDM4EALDH1A1POLBHPGD | |
| Acridine SCHEMBL29774329 | 0.77 | NR4A1 (0.58) | CDC25BKDM4EALDH1A1POLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5723295-A | MULTISTAGE CHEMILUMINESCENT ASSAY WITH PEROXIDASE ENZYME, PH ADJUSTMENT | LUMIGEN, INC. (US) | 1998-03-03 | — | — | US | disclosed |
| US-5670644-A | CHEMILUMINESCENT REACTIONS, PEROXIDASE AND PH FOR IMMUNOASSAY | LUMIGEN, INC. (US) | 1997-09-23 | — | — | US | disclosed |
| EP-0755457-A4 | NOVEL ARYL-N-ALKYLACRIDANTHIOCARBOXYLATE DERIVATIVES USEFUL FOR CHEMILUMINESCENT DETECTION | LUMIGEN INC (US) | 1997-07-16 | — | — | EP | disclosed |
| EP-0755457-A1 | NOVEL ARYL-N-ALKYLACRIDANTHIOCARBOXYLATE DERIVATIVES USEFUL FOR CHEMILUMINESCENT DETECTION | LUMIGEN, INC. (US) | 1997-01-29 | — | — | EP | disclosed |
| US-5523212-A | OXIDATION WITH PEROXIDE AND PEROXIDASE TO EXCITED ACRIDONE DERIVATIVE; DETECTING PROTEINS, HAPTENS, ANTIBODIES, ENZYMES | LUMIGEN, INC. (US) | 1996-06-04 | — | — | US | disclosed |
| WO-1995028495-A1 | NOVEL ARYL-N-ALKYLACRIDANTHIOCARBOXYLATE DERIVATIVES USEFUL FOR CHEMILUMINESCENT DETECTION | LUMIGEN, INC. (US) | 1995-10-26 | — | — | WO | disclosed |