SCHEMBL222908

SCHEMBL222908

O=C(O)c1cccc2nc3ccccc3cc12

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR4A1 P22736 1/20 0.60
NR4A2 P43354 1/20 0.60
NR4A3 Q92570 1/20 0.60
ALDH1A1 P00352 5/20 0.58
KMT2A Q03164 3/20 0.55
KDM4E B2RXH2 3/20 0.55
NPC1 O15118 2/20 0.55
RAB9A P51151 2/20 0.55
GLA P06280 2/20 0.55
HPGD P15428 2/20 0.55
LMNA P02545 2/20 0.55
POLB P06746 1/20 0.55
GAA P10253 1/20 0.55
PTBP1 P26599 1/20 0.55
RCE1 Q9Y256 1/20 0.55
PTPN1 P18031 1/20 0.51
MEN1 O00255 2/20 0.51
TP53 P04637 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2C19 P33261 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acridine SCHEMBL29774329 0.98 NR4A1 (0.58) NR4A1NR4A2NR4A3ALDH1A1KMT2A
Acridine SCHEMBL31147690 0.98 NR4A1 (0.58) NR4A1NR4A2NR4A3ALDH1A1KMT2A
Hydrochloric Acid SCHEMBL9083721 0.98 NR4A1 (0.58) NR4A1NR4A2NR4A3ALDH1A1KMT2A
Water SCHEMBL7769203 0.98 NR4A1 (0.58) NR4A1NR4A2NR4A3ALDH1A1KMT2A
SCHEMBL8850857 0.98 NR4A1 (0.58) NR4A1NR4A2NR4A3ALDH1A1KMT2A
SCHEMBL9424973 0.91 ALDH1A1 (0.53) NR4A1NR4A2NR4A3ALDH1A1KMT2A
SCHEMBL27356901 0.89 ALDH1A1 (0.55) NR4A1NR4A2NR4A3ALDH1A1KMT2A
SCHEMBL5352931 0.87 ALDH1A1 (0.53) NR4A1NR4A2NR4A3ALDH1A1KMT2A
SCHEMBL3296316 0.86 KMT2A (0.54) NR4A1NR4A2NR4A3ALDH1A1KMT2A
SCHEMBL3535241 0.86 ALDH1A1 (0.51) NR4A1NR4A2NR4A3ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 306 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121574095-A Double-band acridine formate anthracene methyl ester photocatalyst and preparation method and application thereof 江西初源新材料有限公司 2026-02-27 CN claimed
WO-2023103464-A1 ZINC TRANSPORTER 8 ANTIBODY CHEMILUMINESCENCE IMMUNOASSAY KIT AND PREPARATION METHOD THEREOF 深圳市亚辉龙生物科技股份有限公司 2023-06-15 WO claimed
CN-106146672-B Acridine marks conjugate and preparation method thereof, chemiluminescence immune detection reagent kit 深圳市亚辉龙生物科技股份有限公司 2019-11-29 CN claimed
US-20190309030-A1 ACRIDINE LABELLED CONJUGATES AND PREPARATION METHODS THEREFOR AND CHEMILUMINESCENT KITS SHENZHEN YHLO BIOTECH CO LTD (CN) 2019-10-10 US claimed
US-20190175566-A1 ANTI-TUMOR COCKTAIL COMPRISING AN ANTI-TUMOR AGENT SELECTIVE FOR TUMOR ACIDITY, AN ANTIOXIDANT, AND A P-GLYCOPROTEIN INHIBITOR ARION TECNOLOGIA BRASIL - GESTÃO DE ATIVOS S/A (BR) 2019-06-13 US claimed
EP-3483172-A1 ACRIDINE-MARKER CONJUGATE AND PREPARATION METHOD THEREOF, AND CHEMILUMINESCENCE KIT Shenzhen Yhlo Biotech Co., Ltd (CN) 2019-05-15 EP claimed
CN-109709336-A A kind of detection kit and detection method of vascular endothelial growth factor 张嘉庆 2019-05-03 CN claimed
CN-107810184-A Light emitting device and compound 圣安德鲁斯大学董事会 2018-03-16 CN claimed
EP-1301485-B1 NOVEL HETEROARYL DERIVATIVES AND THE USE THEREOF AS PHARMACEUTICALS ZENTARIS GMBH (DE) 2007-06-27 EP claimed
US-20050009809-A1 Aryl- and heteroaryl-substituted piperazinylcarbonyl acridines and their homologs, e.g., (1,3-dihydroxyacridin-9-yl)-[4-(6-methyl pyridin-2-yl )piperazin-1-yl]methanone,are suitable for treating benign and malignant tumors ZENTARIS GMBH (DE) 2005-01-13 US claimed
EP-0621788-A4 HEMOREGULATORY PEPTIDES. SMITHKLINE BEECHAM CORP (US) 1997-03-05 EP claimed
EP-0725651-A4 HEMOREGULATORY PEPTIDES SMITHKLINE BEECHAM CORP (US) 1997-03-05 EP claimed
EP-0725651-A1 HEMOREGULATORY PEPTIDES SMITHKLINE BEECHAM CORPORATION (US) 1996-08-14 EP claimed
EP-0701446-A1 HEMOREGULATORY PEPTIDES SMITHKLINE BEECHAM CORPORATION (US) 1996-03-20 EP claimed
WO-1995011693-A1 HEMOREGULATORY PEPTIDES SMITHKLINE BEECHAM CORPORATION (US) 1995-05-04 WO claimed
WO-1994027627-A1 HEMOREGULATORY PEPTIDES SMITHKLINE BEECHAM CORPORATION (US) 1994-12-08 WO claimed
WO-1994028420-A1 METHOD OF DETECTION OF BACTERIA RHONE POULENC DIAGNOSTICS LTD (GB) 1994-12-08 WO claimed
EP-0621788-A1 HEMOREGULATORY PEPTIDES SMITHKLINE BEECHAM CORPORATION (US) 1994-11-02 EP claimed
WO-1993013789-A1 HEMOREGULATORY PEPTIDES SMITHKLINE BEECHAM CORPORATION (US) 1993-07-22 WO claimed
EP-0273115-A2 Chemiluminescent acridinium and phenanthridinium salts ABBOTT LABORATORIES (US) 1988-07-06 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190309030-A1 ACRIDINE LABELLED CONJUGATES AND PREPARATION METHODS THEREFOR AND CHEMILUMINESCENT KITS ACR, GOT1, HLCS NR4A1 3300/4885NR4A2 3996/4885NR4A3 4007/4885
US-20050009809-A1 Aryl- and heteroaryl-substituted piperazinylcarbonyl acridines and their homologs, e.g., (1,3-dihydroxyacridin-9-yl)-[4-(6-methyl pyridin-2-yl )piperazin-1-yl]methanone,are suitable for treating benign and malignant tumors PKD1, MDH2, MSH2 NR4A1 140/4885NR4A2 272/4885NR4A3 540/4885
US-20190175566-A1 ANTI-TUMOR COCKTAIL COMPRISING AN ANTI-TUMOR AGENT SELECTIVE FOR TUMOR ACIDITY, AN ANTIOXIDANT, AND A P-GLYCOPROTEIN INHIBITOR ABCG2, SDHA, ABCB1 NR4A1 3123/4885NR4A2 3271/4885NR4A3 3103/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.