Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | AVPR2 | P30518 | 3/20 | 0.53 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.53 |
| ▸ | OXTR | P30559 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.49 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.49 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.49 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.49 |
| ▸ | BRAF | P15056 | 1/20 | 0.48 |
| ▸ | KIT | P10721 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SNCA | P37840 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7335026 | 0.87 | MITF (0.62) | HDAC1HDAC8HDAC6AVPR2AVPR1A | |
| SCHEMBL3729379 | 0.84 | HDAC8 (0.56) | HDAC8KCNQ3KCNQ2KCNE1KCNQ1 | |
| SCHEMBL7336714 | 0.82 | AVPR2 (0.68) | AVPR2AVPR1AOXTRSMN1; SMN2RAB9A | |
| SCHEMBL7336402 | 0.81 | MEN1 (0.68) | MEN1KMT2ASMN1; SMN2POLBRAB9A | |
| SCHEMBL8859377 | 0.81 | AVPR2 (0.51) | HDAC1HDAC8HDAC6AVPR2AVPR1A | |
| SCHEMBL2571574 | 0.80 | KDM4E (0.53) | MEN1KMT2AKCNQ3KCNQ2KCNE1 | |
| SCHEMBL8859383 | 0.80 | SMN1; SMN2 (0.50) | HDAC1HDAC8HDAC6AVPR2AVPR1A | |
| SCHEMBL18160308 | 0.79 | F10 (0.55) | HDAC1HDAC8HDAC6MEN1KMT2A | |
| SCHEMBL5237637 | 0.79 | HPGD (0.70) | MEN1KMT2ASMN1; SMN2LMNAPOLB | |
| SCHEMBL5946767 | 0.78 | PTPN1 (0.73) | MEN1KMT2AKCNQ3KCNQ2KCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719278-A | TREATING EXCESS RENAL REABSORPTION OF WATER | AMERICAN CYANAMID COMPANY (US) | 1998-02-17 | — | — | US | disclosed |