Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | CASP3 | P42574 | 1/20 | 0.59 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.59 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.59 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | TRPM4 | Q8TD43 | 2/20 | 0.55 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.54 |
| ▸ | G6PD | P11413 | 1/20 | 0.54 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.54 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4912020 | 0.86 | KMT2A (0.60) | HCAR2NPC1KMT2AMEN1CASP3 | |
| SCHEMBL4909117 | 0.85 | HCAR2 (0.56) | HCAR2NPC1KMT2AMEN1CASP3 | |
| SCHEMBL4913355 | 0.83 | L3MBTL1 (0.64) | HCAR2KMT2AMEN1CASP3SENP8 | |
| SCHEMBL4914608 | 0.83 | HCAR2 (0.76) | HCAR2NPC1KMT2AMEN1CASP3 | |
| SCHEMBL4912967 | 0.83 | TRPM4 (0.77) | HCAR2NPC1KMT2AMEN1KDM4E | |
| SCHEMBL8689335 | 0.83 | HSD17B10 (0.77) | HCAR2NPC1KMT2AMEN1CASP3 | |
| SCHEMBL5150684 | 0.83 | MEN1 (0.72) | HCAR2NPC1KMT2AMEN1CASP3 | |
| SCHEMBL4913648 | 0.83 | MEN1 (0.56) | HCAR2NPC1KMT2AMEN1CASP3 | |
| SCHEMBL8691629 | 0.83 | L3MBTL1 (0.64) | HCAR2KMT2AMEN1CASP3SENP8 | |
| SCHEMBL4650476 | 0.82 | HCAR2 (0.59) | HCAR2NPC1KMT2AMEN1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5741926-A | ANTIDIABETIC AGENT | SHAMAN PHARMACEUTICALS, INC. (US) | 1998-04-21 | — | — | US | disclosed |
| WO-1997030019-A1 | ANILINE DERIVATIVES HAVING ANTIHYPERGLYCEMIC ACTIVITY | SHAMAN PHARMACEUTICALS, INC. (US) | 1997-08-21 | — | — | WO | disclosed |