Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ALB | P02768 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | TYMP | P19971 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9471585 | 1.00 | TK1 (0.54) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL10447656 | 1.00 | TK1 (0.54) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL8536696 | 1.00 | TK1 (0.54) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL8536692 | 1.00 | TK1 (0.54) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL8797234 | 1.00 | TK1 (0.54) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL9650744 | 1.00 | TK1 (0.54) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL9471200 | 1.00 | TK1 (0.54) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL9310153 | 0.89 | TK1 (0.60) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL9309847 | 0.88 | TK1 (0.50) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL10514914 | 0.86 | TK1 (0.57) | TK1ALDH1A1LMNAALBPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0335355-B1 | Bis-(hydroxymethyl) cyclobutyl purines and pyrimidines | SQUIBB & SONS INC (US) | 1997-10-01 | — | — | EP | claimed |
| EP-0335355-A2 | Bis-(hydroxymethyl) cyclobutyl purines and pyrimidines | E.R. Squibb & Sons, Inc. (US) | 1989-10-04 | — | — | EP | claimed |
| US-5723609-A | VIRICIDES | E. R. SQUIBB & SONS, INC. (US) | 1998-03-03 | — | — | US | disclosed |
| EP-0335355-B1 | Bis-(hydroxymethyl) cyclobutyl purines and pyrimidines | SQUIBB & SONS INC (US) | 1997-10-01 | — | — | EP | disclosed |
| US-5130462-A | Intermediates for viricides | E. R. SQUIBB & SONS, INC. (US) | 1992-07-14 | — | — | US | disclosed |
| US-5126345-A | Viricides | E. R. SQUIBB & SONS, INC. (US) | 1992-06-30 | — | — | US | disclosed |