Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | BCHE | P06276 | 3/20 | 0.40 |
| ▸ | ACHE | P22303 | 3/20 | 0.40 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.38 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.38 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | CMA1 | P23946 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8124877 | 1.00 | ACE (0.42) | ACEADORA1KMT2ABCHEACHE | |
| Hydrochloric Acid SCHEMBL8691725 | 0.84 | DPP4 (0.41) | ACEADORA1KMT2AF2 | |
| Hydrochloric Acid SCHEMBL8130787 | 0.84 | DPP4 (0.41) | ACEADORA1KMT2AF2 | |
| SCHEMBL8131706 | 0.80 | ACE (0.46) | ACEKMT2ABCHEACHEKLK5 | |
| SCHEMBL8125939 | 0.80 | SCN9A (0.43) | ACEADORA1KMT2AF2PRSS1 | |
| SCHEMBL8690505 | 0.80 | SCN9A (0.43) | ACEADORA1KMT2AF2PRSS1 | |
| SCHEMBL22962152 | 0.73 | ACE (0.59) | ACEKMT2AKLK5F2PRSS1 | |
| SCHEMBL7545974 | 0.72 | ACE (0.58) | ACEKMT2AKLK5F2PRSS1 | |
| SCHEMBL7545907 | 0.72 | ACE (0.58) | ACEKMT2AKLK5F2PRSS1 | |
| SCHEMBL7335472 | 0.72 | ACE (0.49) | ACEBCHEACHEKLK5CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5798352-A | Antithrombotic amidinotetrahydropyridylalanine derivatives | PFIZER INC. (US) | 1998-08-25 | — | — | US | disclosed |