Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
| ▸ | CMA1 | P23946 | 4/20 | 0.46 |
| ▸ | KLK7 | P49862 | 1/20 | 0.44 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.44 |
| ▸ | TLR2 | O60603 | 1/20 | 0.44 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.44 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.44 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.44 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.44 |
| ▸ | CTRC | Q99895 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | CCKBR | P32239 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7352624 | 0.87 | PPARA (0.56) | ACECTSLCMA1KLK7KLK5 | |
| SCHEMBL1815101 | 0.84 | ACE (0.55) | ACECTSLITGB3ITGA2BCMA1 | |
| SCHEMBL7335071 | 0.83 | AGTR2 (0.42) | ACECTSLCMA1 | |
| SCHEMBL29131321 | 0.80 | ACE (0.65) | ACECTSLCMA1KLK7KLK5 | |
| SCHEMBL29131320 | 0.80 | ACE (0.65) | ACECTSLCMA1KLK7KLK5 | |
| SCHEMBL7533944 | 0.80 | ACE (0.65) | ACECTSLCMA1KLK7KLK5 | |
| SCHEMBL20701384 | 0.80 | KLK7 (0.44) | ACECTSLITGB3ITGA2BCMA1 | |
| SCHEMBL21619214 | 0.80 | KLK7 (0.44) | ACECTSLITGB3ITGA2BCMA1 | |
| SCHEMBL20701381 | 0.80 | KLK7 (0.44) | ACECTSLITGB3ITGA2BCMA1 | |
| SCHEMBL21619213 | 0.80 | KLK7 (0.44) | ACECTSLITGB3ITGA2BCMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5371091-A | Anticoagulants | BRISTOL-MYERS SQUIBB COMPANY (US) | 1994-12-06 | — | — | US | disclosed |