Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | APAF1 | O14727 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | CA7 | P43166 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.39 |
| ▸ | EPAS1 | Q99814 | 6/20 | 0.39 |
| ▸ | TSSK1B | Q9BXA7 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7102356 | 1.00 | ALDH1A1 (0.55) | ALDH1A1APAF1MAPK1NPSR1CA12 | |
| SCHEMBL8689317 | 1.00 | ALDH1A1 (0.55) | ALDH1A1APAF1MAPK1NPSR1CA12 | |
| SCHEMBL8692709 | 1.00 | ALDH1A1 (0.55) | ALDH1A1APAF1MAPK1NPSR1CA12 | |
| SCHEMBL6688542 | 0.90 | ALDH1A1 (0.51) | ALDH1A1APAF1MAPK1NPSR1CA12 | |
| SCHEMBL6653961 | 0.89 | ALDH1A1 (0.55) | ALDH1A1APAF1MAPK1NPSR1CA12 | |
| SCHEMBL7099007 | 0.83 | ALDH1A1 (0.50) | ALDH1A1APAF1MAPK1NPSR1CA12 | |
| SCHEMBL7103086 | 0.83 | ALDH1A1 (0.50) | ALDH1A1APAF1MAPK1NPSR1CA12 | |
| SCHEMBL7103952 | 0.83 | ALDH1A1 (0.50) | ALDH1A1APAF1MAPK1NPSR1CA12 | |
| SCHEMBL6675540 | 0.83 | ALDH1A1 (0.57) | ALDH1A1APAF1MAPK1NPSR1CA12 | |
| Calanolide A SCHEMBL140017 | 0.71 | ALDH1A1 (1.00) | ALDH1A1APAF1MAPK1NPSR1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843990-A | Pyran-chromenone compounds, their synthesis and anti-HIV activity | THE UNIVERSITY OF TENNESSEE RESEARCH CORPORATION (US) | 1998-12-01 | — | — | US | disclosed |