Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8690626 | 0.80 | MMP8 (0.48) | MEN1KMT2ASMN1; SMN2MMEMAPK1 | |
| SCHEMBL8693477 | 0.79 | KMT2A (0.43) | MEN1KMT2ASMN1; SMN2ALDH1A1MME | |
| SCHEMBL8692827 | 0.79 | KMT2A (0.43) | MEN1KMT2AALDH1A1MMEACE | |
| SCHEMBL8693497 | 0.78 | MEN1 (0.44) | MEN1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL4807741 | 0.76 | KMT2A (0.42) | MEN1KMT2ASMN1; SMN2HTTMME | |
| SCHEMBL4940887 | 0.75 | SOAT1 (0.41) | ALDH1A1GAA | |
| SCHEMBL15262442 | 0.74 | MEN1 (0.52) | MEN1KMT2AALDH1A1HTTGAA | |
| SCHEMBL8690484 | 0.73 | KMT2A (0.49) | MEN1KMT2ASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL3232085 | 0.72 | MAPT (0.50) | MEN1KMT2ASMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL13495167 | 0.71 | MMP8 (0.50) | MEN1KMT2ASMN1; SMN2ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827863-A | Pyrazole derivatives as angiotensin II antagonists | J. URIACH & CIA, S.A. (ES) | 1998-10-27 | — | — | US | disclosed |
| EP-0721454-A1 | NEW PYRAZOLE DERIVATIVES AS ANGIOTENSIN II ANTAGONIST | J. URIACH & CIA. S.A. (ES) | 1996-07-17 | — | — | EP | disclosed |
| WO-1996004273-A1 | NEW PYRAZOLE DERIVATIVES AS ANGIOTENSIN II ANTAGONIST | J. URIACH & CIA, S.A. (ES) | 1996-02-15 | — | — | WO | disclosed |