Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | NAAA | Q02083 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8692169 | 1.00 | HDAC8 (0.52) | HDAC8HDAC6NAAAEPHX1HSD17B10 | |
| SCHEMBL8691320 | 0.98 | HSD17B10 (0.48) | HDAC8HDAC6NAAAEPHX1HSD17B10 | |
| SCHEMBL8690930 | 0.93 | HSD17B10 (0.44) | HDAC8HDAC6NAAAEPHX1HSD17B10 | |
| SCHEMBL5509671 | 0.89 | — | — | |
| SCHEMBL8693480 | 0.86 | NAAA (0.50) | HDAC8HDAC6NAAAEPHX1HSD17B10 | |
| SCHEMBL8694321 | 0.86 | NAAA (0.50) | HDAC8HDAC6NAAAEPHX1HSD17B10 | |
| SCHEMBL8690422 | 0.83 | NAAA (0.47) | HDAC8HDAC6NAAAEPHX1HSD17B10 | |
| SCHEMBL4390736 | 0.80 | HDAC8 (0.54) | HDAC8HDAC6NAAAEPHX1HSD17B10 | |
| SCHEMBL8696663 | 0.80 | HDAC8 (0.54) | HDAC8HDAC6NAAAEPHX1HSD17B10 | |
| SCHEMBL13652728 | 0.80 | NAAA (0.41) | HDAC8HDAC6NAAAEPHX1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827863-A | Pyrazole derivatives as angiotensin II antagonists | J. URIACH & CIA, S.A. (ES) | 1998-10-27 | — | — | US | disclosed |
| EP-0721454-A1 | NEW PYRAZOLE DERIVATIVES AS ANGIOTENSIN II ANTAGONIST | J. URIACH & CIA. S.A. (ES) | 1996-07-17 | — | — | EP | disclosed |
| WO-1996004273-A1 | NEW PYRAZOLE DERIVATIVES AS ANGIOTENSIN II ANTAGONIST | J. URIACH & CIA, S.A. (ES) | 1996-02-15 | — | — | WO | disclosed |