Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.59 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.59 |
| ▸ | LTA4H | P09960 | 7/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.51 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.50 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8693005 | 0.94 | TMEM97 (0.60) | TMEM97SIGMAR1LTA4HKDM4EKCNA5 | |
| SCHEMBL22266173 | 0.86 | LTA4H (0.71) | TMEM97SIGMAR1LTA4HKDM4EALDH1A1 | |
| SCHEMBL5031358 | 0.83 | HRH3 (0.53) | TMEM97SIGMAR1LTA4HKDM4EALDH1A1 | |
| SCHEMBL5029372 | 0.81 | HRH3 (0.56) | TMEM97SIGMAR1LTA4HKDM4EALDH1A1 | |
| SCHEMBL14204982 | 0.80 | LTA4H (0.81) | TMEM97SIGMAR1LTA4HKDM4EKCNA5 | |
| SCHEMBL22266214 | 0.79 | LTA4H (0.62) | TMEM97SIGMAR1LTA4HKDM4EALDH1A1 | |
| SCHEMBL8693762 | 0.79 | TMEM97 (0.68) | TMEM97SIGMAR1LTA4H | |
| SCHEMBL8691198 | 0.79 | TMEM97 (0.60) | TMEM97SIGMAR1LTA4HKCNH2 | |
| SCHEMBL3571383 | 0.78 | TMEM97 (0.71) | TMEM97SIGMAR1LTA4HHTR1AHTR7 | |
| SCHEMBL27877049 | 0.78 | TMEM97 (0.74) | TMEM97SIGMAR1KDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5760035-A | PIPERIDINE COMPOUNDS SUBSTITUTED WITH AN AMINOALKYL GROUP AND AN ARYLOXYALKYL GROUP, ANTIALLERGENS, ANTIINFLAMMATORY AGENTS, IMMUNOSUPPRESSANTS | KNOLL AKTIENGESELLSCHAFT (DE) | 1998-06-02 | — | — | US | disclosed |