Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 6/20 | 0.53 |
| ▸ | PPARA | Q07869 | 3/20 | 0.53 |
| ▸ | CCR2 | P41597 | 3/20 | 0.47 |
| ▸ | PPARG | P37231 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.42 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8686793 | 0.89 | FFAR1 (0.47) | FFAR1PPARAPPARGMAPTALDH1A1 | |
| SCHEMBL97359 | 0.80 | FFAR1 (0.48) | FFAR1PPARACCR2PPARGMAPT | |
| SCHEMBL13846729 | 0.80 | DDB1 (0.56) | FFAR1PPARAPPARGMAPTALDH1A1 | |
| SCHEMBL97460 | 0.79 | PPARG (0.49) | FFAR1PPARACCR2PPARGMAPT | |
| SCHEMBL8690850 | 0.76 | CCR2 (0.44) | CCR2PPARGALDH1A1KDM4EGAA | |
| SCHEMBL8686619 | 0.74 | FFAR1 (0.57) | FFAR1PPARAPPARGMAPTALDH1A1 | |
| SCHEMBL166570 | 0.74 | PPARG (0.74) | FFAR1PPARAPPARGMAPTALDH1A1 | |
| SCHEMBL100284 | 0.73 | FFAR1 (0.50) | FFAR1PPARAPPARGMAPTALDH1A1 | |
| SCHEMBL8685001 | 0.72 | FFAR1 (0.58) | FFAR1PPARAPPARGMAPTALDH1A1 | |
| SCHEMBL31402270 | 0.72 | CCR2 (0.59) | CCR2PPARGALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811439-A | ANTIDIABETIC AGENTS; SIDE EFFECT REDUCTION; ANTILEPEMIC AGENTS | SENGA PHARMACEUTICAL LABORATORY INC. (JP) | 1998-09-22 | — | — | US | disclosed |
| EP-0780389-A1 | Thiazolidinedione derivatives, process for their preparation and pharmaceutical compositions containing them | TOBISHI PHARMACEUTICAL CO., LTD. (JP) | 1997-06-25 | — | — | EP | disclosed |