SCHEMBL8690876

SCHEMBL8690876

CCCCCCCCCCCCCCCCCCCC(N)(CCO)CCO

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.48
ALDH1A1 P00352 2/20 0.48
HSD17B10 Q99714 1/20 0.48
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
TSHR P16473 1/20 0.48
SMPD1 P17405 4/20 0.47
FDPS P14324 3/20 0.47
SMN1; SMN2 Q16637 1/20 0.43
TNNC1 P63316 5/20 0.43
S1PR1 P21453 2/20 0.43
SGPL1 O95470 1/20 0.43
S1PR4 O95977 1/20 0.43
GPR183 P32249 1/20 0.43
CERS2 Q96G23 1/20 0.43
S1PR3 Q99500 1/20 0.43
S1PR5 Q9H228 1/20 0.43
GGPS1 O95749 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3069297 1.00 LMNA (0.48) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL4461494 1.00 LMNA (0.48) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL8685973 1.00 LMNA (0.48) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL8830314 1.00 LMNA (0.48) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL1421830 1.00 LMNA (0.48) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL3069042 1.00 LMNA (0.48) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL9575104 1.00 LMNA (0.48) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL3070711 1.00 LMNA (0.48) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL221427 1.00 LMNA (0.48) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL918621 1.00 LMNA (0.48) LMNAALDH1A1HSD17B10MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4529528-A Reacting an alkoxylated amine and a phosphite MOBIL OIL CORPORATION (US) 1985-07-16 US claimed
US-5824626-A Process for preparing trithianes and phosphorus acid and/or thiophosphorus acid derivatives THE LUBRIZOL CORPORATION (US) 1998-10-20 US disclosed
EP-0522133-B1 TRITHIANES AND PHOSPHORUS ACID AND/OR THIOPHOSPHORUS ACID DERIVATIVES LUBRIZOL CORP (US) 1995-08-30 EP disclosed
US-5194166-A Phosphorous amine lubricant additives THE ELCO CORPORATION (US) 1993-03-16 US disclosed
US-5182037-A PHOSPHORUS- AND/OR NITROGEN-CONTAINING DERIVATIVES OF SULFUR-CONTAINING COMPOUNDS, LUBRICANT, FUEL AND FUNCTIONAL FLUID COMPOSITIONS THE LUBRIZOL CORPORATION (US) 1993-01-26 US disclosed
EP-0522133-A1 TRITHIANES AND PHOSPHORUS ACID AND/OR THIOPHOSPHORUS ACID DERIVATIVES. LUBRIZOL CORP (US) 1993-01-13 EP disclosed
EP-0318511-B1 BORATED AMINE SALTS OF MONOTHIOPHOSPHORIC ACIDS The Lubrizol Corporation (US) 1992-09-23 EP disclosed
WO-1992012225-A1 TRITHIANES AND PHOSPHORUS ACID AND/OR THIOPHOSPHORUS ACID DERIVATIVES THE LUBRIZOL CORPORATION (US) 1992-07-23 WO disclosed
US-5130036-A Friction reducing phosphorous alkoxylated amine lubricants THE ELCO CORPORATION (US) 1992-07-14 US disclosed
EP-0289592-B1 PHOSPHORUS- AND/OR NITROGEN-CONTAINING DERIVATIVES IN LUBRICANT COMPOSITIONS The Lubrizol Corporation (US) 1992-06-24 EP disclosed
EP-0325977-B1 PHOSPHITE AMINE LUBRICANT ADDITIVES THE ELCO CORPORATION (US) 1992-03-25 EP disclosed
EP-0456888-A1 Phosphorous amine lubricant additives THE ELCO CORPORATION (US) 1991-11-21 EP disclosed
US-4992184-A Reaction product of arylsulfonic acid and (diol or amine) phosphite MOBIL OIL CORPORATION (US) 1991-02-12 US disclosed
US-4965002-A Reaction product of alkoxylated amine and organic phosphize ELCO CORPORATION (US) 1990-10-23 US disclosed
EP-0325977-A1 Phosphite amine lubricant additives THE ELCO CORPORATION (US) 1989-08-02 EP disclosed
EP-0309486-A1 PHOSPHOROUS- AND SULFUR-CONTAINING LUBRICANT AND FUNCTIONAL FLUID COMPOSITIONS The Lubrizol Corporation (US) 1989-04-05 EP disclosed
US-4755311-A Borated amine salt of dihydrocarbyl monothiophosphoric acid THE LUBRIZOL CORPORATION (US) 1988-07-05 US disclosed
WO-1987007638-A2 PHOSPHOROUS- AND SULFUR-CONTAINING LUBRICANT AND FUNCTIONAL FLUID COMPOSITIONS THE LUBRIZOL CORPORATION (US) 1987-12-17 WO disclosed
US-4557845-A FRICTION REDUCERS AND FUEL CONSUMPTION REDUCERS MOBIL OIL CORPORATION (US) 1985-12-10 US disclosed
US-4529528-A Reacting an alkoxylated amine and a phosphite MOBIL OIL CORPORATION (US) 1985-07-16 US disclosed