Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 18/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.60 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7884157 | 1.00 | HTR1A (0.60) | HTR1ASLC6A4ADRA1DADRA1AADRA1B | |
| SCHEMBL7885650 | 0.94 | HTR1A (0.59) | HTR1ASLC6A4ADRA1DADRA1AADRA1B | |
| SCHEMBL8695915 | 0.94 | HTR1A (0.59) | HTR1ASLC6A4ADRA1DADRA1AADRA1B | |
| SCHEMBL7883019 | 0.92 | HTR1A (0.60) | HTR1ASLC6A4ADRA1DADRA1AADRA1B | |
| SCHEMBL8694826 | 0.91 | HTR1A (0.59) | HTR1ASLC6A4ADRA1DADRA1AADRA1B | |
| SCHEMBL7885660 | 0.91 | HTR1A (0.59) | HTR1ASLC6A4ADRA1DADRA1AADRA1B | |
| SCHEMBL7885557 | 0.90 | HTR1A (0.57) | HTR1ASLC6A4ADRA1DADRA1AADRA1B | |
| SCHEMBL8696595 | 0.90 | HTR1A (0.57) | HTR1ASLC6A4ADRA1DADRA1AADRA1B | |
| SCHEMBL8695028 | 0.90 | HTR1A (0.58) | HTR1ASLC6A4ADRA1DADRA1AADRA1B | |
| SCHEMBL8872506 | 0.90 | HTR1A (0.58) | HTR1ASLC6A4ADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5789402-A | Compounds having effects on serotonin-related systems | ELI LILLY COMPANY (US) | 1998-08-04 | — | — | US | disclosed |
| US-5741789-A | HETERO-OXY ALKANAMINES | ELI LILLY AND COMPANY (US) | 1998-04-21 | — | — | US | disclosed |