Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.65 |
| ▸ | HRH2 | P25021 | 1/20 | 0.58 |
| ▸ | HRH1 | P35367 | 1/20 | 0.58 |
| ▸ | ACP1 | P24666 | 9/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8691834 | 0.90 | HRH3 (0.58) | HRH3MEN1KMT2A | |
| SCHEMBL8694610 | 0.88 | KDM4E (0.67) | HRH3ACP1MEN1KMT2A | |
| SCHEMBL8692776 | 0.87 | SLC2A1 (0.56) | HRH3MEN1KMT2A | |
| SCHEMBL8692258 | 0.85 | KDM4E (0.62) | HRH3ACP1MEN1KMT2A | |
| SCHEMBL7207251 | 0.84 | KDM4E (0.51) | HRH3HRH1KMT2A | |
| Bromide SCHEMBL7207307 | 0.83 | DRD2 (0.50) | HRH3HRH1KMT2A | |
| Bromide SCHEMBL7209939 | 0.82 | KDM4E (0.51) | HRH1 | |
| SCHEMBL8691758 | 0.81 | CHRM1 (0.63) | ACP1MEN1KMT2A | |
| SCHEMBL491641 | 0.81 | ACP1 (0.70) | HRH3ACP1 | |
| Bromide SCHEMBL7210682 | 0.80 | DRD2 (0.54) | HRH3HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5770734-A | N-substituted-2-aminoquinolines useful for treating hypofunction of the cholinergic system | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-06-23 | — | — | US | claimed |
| US-5770734-A | N-substituted-2-aminoquinolines useful for treating hypofunction of the cholinergic system | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-06-23 | — | — | US | disclosed |
| US-5149815-A | Anticholirergic agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-09-22 | — | — | US | disclosed |
| US-5093333-A | N-substituted-2-aminoquinolines useful for treating hypofunction of the cholinergic system | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-03-03 | — | — | US | disclosed |