Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 9/20 | 0.45 |
| ▸ | PPARA | Q07869 | 9/20 | 0.45 |
| ▸ | PPARD | Q03181 | 4/20 | 0.45 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | CPA1 | P15085 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27337151 | 0.87 | MME (0.49) | PPARAMMEACECYP1A2CYP3A4 | |
| SCHEMBL8692217 | 0.85 | LDHA (0.50) | ACACBPPARGPPARACYP1A2CYP2D6 | |
| SCHEMBL8695465 | 0.85 | ACACB (0.45) | ACACBFFAR1PPARGPPARAMME | |
| SCHEMBL8695716 | 0.83 | ACACB (0.48) | ACACBPPARA | |
| SCHEMBL8694777 | 0.81 | PPARA (0.53) | ACACBFFAR1PPARGPPARAPPARD | |
| SCHEMBL8861640 | 0.81 | PPARA (0.53) | ACACBFFAR1PPARGPPARAPPARD | |
| SCHEMBL8692294 | 0.79 | FFAR1 (0.46) | ACACBFFAR1PPARGPPARAPPARD | |
| SCHEMBL8694880 | 0.76 | FFAR1 (0.46) | ACACBFFAR1PPARGPPARAPPARD | |
| SCHEMBL17539605 | 0.72 | FFAR1 (0.57) | ACACBFFAR1PPARGPPARAPPARD | |
| SCHEMBL8695484 | 0.72 | SLC1A1 (0.44) | PPARGPPARAMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846956-A | Amino acids derivatives, the process for their preparation and their applications to therapy | SOCIETE CIVILE BIOPROJET (FR) | 1998-12-08 | — | — | US | disclosed |