Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HMGB1 | P09429 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | CDC25B | P30305 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7987374 | 0.80 | MAPT (0.42) | ALDH1A1KMT2ACA1CA2SMN1; SMN2 | |
| SCHEMBL7987377 | 0.80 | MAPT (0.42) | ALDH1A1KMT2ACA1CA2SMN1; SMN2 | |
| SCHEMBL7992464 | 0.73 | — | — | |
| SCHEMBL7992462 | 0.73 | — | — | |
| SCHEMBL8693305 | 0.70 | MAPT (0.41) | ALDH1A1KMT2ACA1CA2SMN1; SMN2 | |
| SCHEMBL30339401 | 0.70 | ALDH1A1 (0.56) | ALDH1A1ALOX15KDM4EHMGB1HPGD | |
| SCHEMBL722115 | 0.70 | ALDH1A1 (0.56) | ALDH1A1ALOX15KDM4EHMGB1HPGD | |
| Water SCHEMBL28274877 | 0.69 | ALDH1A1 (0.54) | ALDH1A1ALOX15KDM4EHMGB1HPGD | |
| SCHEMBL1690946 | 0.68 | ALDH1A1 (0.39) | ALDH1A1ALOX15KDM4EHMGB1HPGD | |
| SCHEMBL3785117 | 0.68 | KMT2A (0.34) | ALDH1A1KMT2ASMN1; SMN2MEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5747522-A | ANTICOAGULANTS; ANTIINFLAMMATORY AGENTS; ANTITUMOR AGENTS | HOFFMAN-LA ROCHE INC. (US) | 1998-05-05 | — | — | US | disclosed |
| US-5670515-A | TREATMENT OF THROMBOSIS, STROKE, CARDIAC INFARCT, INFLAMMATION, AND ARTERIOSCLEROSIS; ANTITUMOR AGENTS, WOUND HEALING AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1997-09-23 | — | — | US | disclosed |