⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2186150 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL2185623 | 0.97 | — | — | |
| SCHEMBL464768 | 0.79 | — | — | |
| SCHEMBL5713341 | 0.77 | DAO (0.50) | — | |
| SCHEMBL1651954 | 0.77 | FDPS (0.45) | — | |
| SCHEMBL1426071 | 0.75 | — | — | |
| SCHEMBL10680 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL3789712 | 0.74 | GAA (0.40) | — | |
| Bromide SCHEMBL714157 | 0.72 | — | — | |
| SCHEMBL5384 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119859155-A | Tri-fused ring derivative inhibitor, preparation method and application thereof | 江苏豪森药业集团有限公司 | 2025-04-22 | — | — | CN | disclosed |
| EP-4389754-A1 | METAL-ORGANIC COORDINATION COMPOUND AND METHOD FOR PRODUCING THE SAME | beeOLED GmbH (DE) | 2024-06-26 | — | — | EP | disclosed |
| CN-110536884-B | Synthesis of MCL-1 inhibitors | 阿斯利康(瑞典)有限公司 | 2023-05-02 | — | — | CN | disclosed |
| EP-3131897-B1 | FACTOR IXA INHIBITORS | MERCK SHARP & DOHME (US) | 2022-06-15 | — | — | EP | disclosed |
| EP-3601230-B1 | SYNTHESIS OF MCL-1 INHIBITOR | ASTRAZENECA AB (SE) | 2022-01-26 | — | — | EP | disclosed |
| US-11149024-B2 | Synthesis of Mcl-1 inhibitor | ASTRAZENECA AB (SE) | 2021-10-19 | — | — | US | disclosed |
| US-20210122735-A1 | SYNTHESIS OF MCL-1 INHIBITOR | ASTRAZENECA AB (SE) | 2021-04-29 | — | — | US | disclosed |
| EP-3601230-A1 | SYNTHESIS OF MCL-1 INHIBITOR | Astrazeneca AB (SE) | 2020-02-05 | — | — | EP | disclosed |
| CN-106255689-B | Heteroaryl SYK Inhibitors | 勃林格殷格翰国际有限公司 | 2019-09-17 | — | — | CN | disclosed |
| CN-110183440-A | Heteroaryl SYK inhibitor | 勃林格殷格翰国际有限公司 | 2019-08-30 | — | — | CN | disclosed |
| US-4663462-A | CHEMICAL INTERMEDIATES FOR HYPOTENSIVES AND ADRENERGIC BLOCK AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1987-05-05 | — | — | US | disclosed |
| US-4657579-A | HERBICIDE | SANDOZ LTD. (CH) | 1987-04-14 | — | — | US | disclosed |
| US-4577030-A | Azolyl-substituted phenoxy-aminopropanol derivatives | HOFFMANN-LA ROCHE INC. (US) | 1986-03-18 | — | — | US | disclosed |
| EP-0034831-B1 | SUBSTITUTED PHENOXY-AMINOPROPANOL DERIVATIVES, INTERMEDIATES AND PROCESS FOR THEIR PREPARATION AND MEDICAMENT CONTAINING THEM | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1984-12-12 | — | — | EP | disclosed |
| US-4387100-A | AROMATIC N-HETEROCYCLES, ADRENERGIC BLOCKING AGENTS, HYPOTENSIVE AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1983-06-07 | — | — | US | disclosed |
| EP-0069848-A2 | Substituted phenoxyphenyl-azolylalkyl ethers, process for their preparation and their application as herbicides and as plant growth regulators | BAYER AG (DE) | 1983-01-19 | — | — | EP | disclosed |
| EP-0069881-A1 | S-azolyl-methyl-di(tri)-thiophosphoric-acid esters, process for their preparation and their use as pesticides | BAYER AG (DE) | 1983-01-19 | — | — | EP | disclosed |
| US-4325962-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIDYRETICS | BYK-GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1982-04-20 | — | — | US | disclosed |
| EP-0034831-A2 | Substituted phenoxy-aminopropanol derivatives, intermediates and process for their preparation and medicament containing them | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1981-09-02 | — | — | EP | disclosed |
| US-4146721-A | ANALGESICS, ANTIINFLAMMATORY AGENTS AND ANTIPYRETICS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1979-03-27 | — | — | US | disclosed |