Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 2/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8693865 | 0.92 | EPHX1 (0.42) | EPHX1NAAACYP19A1 | |
| SCHEMBL450993 | 0.92 | EPHX1 (0.46) | EPHX1NAAACYP19A1ALDH1A1 | |
| SCHEMBL8579933 | 0.90 | EPHX1 (0.49) | EPHX1NAAACYP19A1ALDH1A1 | |
| SCHEMBL453873 | 0.90 | EPHX1 (0.49) | EPHX1NAAACYP19A1ALDH1A1 | |
| SCHEMBL8691321 | 0.84 | NAAA (0.36) | EPHX1NAAAALDH1A1 | |
| SCHEMBL1568468 | 0.79 | CYP19A1 (0.44) | EPHX1NAAACYP19A1 | |
| SCHEMBL8691006 | 0.77 | NAAA (0.41) | EPHX1NAAAALDH1A1 | |
| SCHEMBL450932 | 0.77 | NAAA (0.45) | EPHX1NAAACYP19A1ALDH1A1 | |
| SCHEMBL8630969 | 0.76 | NAAA (0.46) | EPHX1NAAACYP19A1ALDH1A1 | |
| SCHEMBL451498 | 0.76 | NAAA (0.46) | EPHX1NAAACYP19A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827863-A | Pyrazole derivatives as angiotensin II antagonists | J. URIACH & CIA, S.A. (ES) | 1998-10-27 | — | — | US | disclosed |
| EP-0721454-A1 | NEW PYRAZOLE DERIVATIVES AS ANGIOTENSIN II ANTAGONIST | J. URIACH & CIA. S.A. (ES) | 1996-07-17 | — | — | EP | disclosed |
| WO-1996004273-A1 | NEW PYRAZOLE DERIVATIVES AS ANGIOTENSIN II ANTAGONIST | J. URIACH & CIA, S.A. (ES) | 1996-02-15 | — | — | WO | disclosed |