Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NPY1R | P25929 | 1/20 | 0.33 |
| ▸ | NPY2R | P49146 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7841807 | 1.00 | NPSR1 (0.42) | NPSR1CYP2D6ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL7850181 | 0.88 | NPSR1 (0.45) | NPSR1CYP2D6ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL8695480 | 0.81 | NPSR1 (0.43) | NPSR1CYP2D6ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL8694662 | 0.80 | NPSR1 (0.42) | NPSR1CYP2D6ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL7841742 | 0.80 | NPSR1 (0.42) | NPSR1CYP2D6ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL8693549 | 0.79 | NPSR1 (0.42) | NPSR1CYP2D6ALDH1A1MAPTCYP1A2 | |
| SCHEMBL7842408 | 0.79 | DHODH (0.51) | NPSR1CYP2D6ALDH1A1MAPTCYP1A2 | |
| SCHEMBL7849686 | 0.79 | NPSR1 (0.40) | NPSR1CYP2D6ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL8693119 | 0.79 | DHODH (0.51) | NPSR1CYP2D6ALDH1A1MAPTCYP1A2 | |
| SCHEMBL7850372 | 0.79 | NPSR1 (0.41) | NPSR1CYP2D6ALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811433-A | ANTIMICROBIALS | BAYER AKTIENGESELLSCHAFT (DE) | 1998-09-22 | — | — | US | disclosed |