Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD2 | Q15562 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.34 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PDE5A | O76074 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | IKBKB | O14920 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8696094 | 0.93 | TEAD2 (0.38) | TEAD2KMT2AKDM4EHPGDBAZ2B | |
| SCHEMBL8693715 | 0.88 | TEAD2 (0.40) | TEAD2KMT2AHCAR2KDM4EHPGD | |
| SCHEMBL8693052 | 0.88 | TEAD2 (0.40) | TEAD2KMT2AHCAR2KDM4EHPGD | |
| SCHEMBL8696818 | 0.85 | HTT (0.41) | TEAD2KMT2AHCAR2KDM4ETSHR | |
| SCHEMBL8693502 | 0.84 | ALDH1A1 (0.46) | TEAD2KMT2AKDM4ETSHRMAPT | |
| SCHEMBL8696011 | 0.84 | KDM4E (0.40) | TEAD2KMT2AKDM4EHPGDBAZ2B | |
| SCHEMBL8694568 | 0.83 | TEAD2 (0.39) | TEAD2KMT2AHCAR2KDM4EHPGD | |
| SCHEMBL8692506 | 0.83 | TEAD2 (0.39) | TEAD2KMT2AHCAR2KDM4EHPGD | |
| SCHEMBL8693098 | 0.82 | HTT (0.43) | TEAD2KMT2AHCAR2KDM4ETSHR | |
| SCHEMBL8696080 | 0.82 | TEAD2 (0.41) | TEAD2KMT2AHCAR2KDM4EBAZ2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849779-A | Pyrazole derivatives and their pharmaceutical use | JAPAN ENERGY CORPORATION (JP) | 1998-12-15 | — | — | US | disclosed |
| EP-0810217-A1 | Pyrazole derivatives and their pharmaceutical use as smooth muscle cell growth inhibitors | JAPAN ENERGY CORPORATION (JP) | 1997-12-03 | — | — | EP | disclosed |