Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A1 | P30531 | 4/20 | 0.61 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL8789294 | 0.96 | SLC6A1 (0.65) | SLC6A1KDM4EALDH1A1 | |
| Oxalic Acid SCHEMBL8789284 | 0.96 | SLC6A1 (0.65) | SLC6A1KDM4EALDH1A1 | |
| SCHEMBL9079027 | 0.94 | SLC6A1 (0.67) | SLC6A1SLC6A11 | |
| SCHEMBL8788557 | 0.94 | SLC6A1 (0.67) | SLC6A1SLC6A11 | |
| Hydrochloric Acid SCHEMBL8910227 | 0.93 | SLC6A1 (0.66) | SLC6A1 | |
| Hydrochloric Acid SCHEMBL8910236 | 0.93 | SLC6A1 (0.66) | SLC6A1 | |
| SCHEMBL9079900 | 0.86 | KDM4E (0.63) | KDM4EALDH1A1 | |
| SCHEMBL9079896 | 0.86 | KDM4E (0.63) | KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL8909836 | 0.85 | — | — | |
| Hydrochloric Acid SCHEMBL8909832 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5760035-A | PIPERIDINE COMPOUNDS SUBSTITUTED WITH AN AMINOALKYL GROUP AND AN ARYLOXYALKYL GROUP, ANTIALLERGENS, ANTIINFLAMMATORY AGENTS, IMMUNOSUPPRESSANTS | KNOLL AKTIENGESELLSCHAFT (DE) | 1998-06-02 | — | — | US | disclosed |
| EP-0720602-A1 | 4-ALKYLAMINO-1-PHENOXYALKYL PIPERIDINES AS ANTIINFLAMMATORY, ANTIALLERGIC AND IMMUNOMODULATING AGENTS | KNOLL AG (DE) | 1996-07-10 | — | — | EP | disclosed |
| WO-1995008535-A1 | 4-ALKYLAMINO-1-PHENOXYALKYL PIPERIDINES AS ANTIINFLAMMATORY, ANTIALLERGIC AND IMMUNOMODULATING AGENTS | KNOLL AG (DE) | 1995-03-30 | — | — | WO | disclosed |