SCHEMBL869480

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL869003	0.93	RIPK1 (0.87)	RIPK1EIF2AK3EIF2AK2EIF2AK1
	SCHEMBL868494	0.91	RIPK1 (1.00)	RIPK1EIF2AK3EIF2AK2EIF2AK1
	SCHEMBL870134	0.91	RIPK1 (0.84)	RIPK1EIF2AK3
	SCHEMBL868624	0.90	RIPK1 (1.00)	RIPK1EIF2AK3
	SCHEMBL868187	0.89	RIPK1 (1.00)	RIPK1EIF2AK3
	SCHEMBL869083	0.89	RIPK1 (0.84)	RIPK1EIF2AK3EIF2AK2EIF2AK1
	SCHEMBL868466	0.88	RIPK1 (1.00)	RIPK1EIF2AK3EIF2AK2EIF2AK1
	SCHEMBL868450	0.87	RIPK1 (0.86)	RIPK1EIF2AK3
	Trifluoroacetic Acid SCHEMBL869460	0.86	RIPK1 (0.81)	RIPK1EIF2AK3EIF2AK2EIF2AK1
	SCHEMBL868690	0.86	RIPK1 (0.77)	RIPK1EIF2AK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.