Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | PHGDH | O43175 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Piperazine SCHEMBL27903046 | 1.00 | HTR6 (0.61) | HTR6KMT2AHPGDSMN1; SMN2HRH3 | |
| SCHEMBL28809524 | 1.00 | HTR6 (0.61) | HTR6KMT2AHPGDSMN1; SMN2HRH3 | |
| SCHEMBL943337 | 0.97 | HTR6 (0.64) | HTR6KMT2AHPGDSMN1; SMN2HRH3 | |
| SCHEMBL43171 | 0.97 | HTR6 (0.64) | HTR6KMT2AHPGDSMN1; SMN2HRH3 | |
| SCHEMBL451992 | 0.97 | HTR6 (0.64) | HTR6KMT2AHPGDSMN1; SMN2HRH3 | |
| SCHEMBL1267270 | 0.97 | HTR6 (0.64) | HTR6KMT2AHPGDSMN1; SMN2HRH3 | |
| Hydrochloric Acid SCHEMBL6499302 | 0.95 | HTR6 (0.61) | HTR6KMT2AHPGDSMN1; SMN2HRH3 | |
| Water SCHEMBL14860181 | 0.95 | HTR6 (0.61) | HTR6KMT2AHPGDSMN1; SMN2HRH3 | |
| Hydrochloric Acid SCHEMBL572044 | 0.95 | HTR6 (0.61) | HTR6KMT2AHPGDSMN1; SMN2HRH3 | |
| SCHEMBL271868 | 0.95 | HTR6 (0.67) | HTR6KMT2AHPGDSMN1; SMN2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5721361-A | CONTACTING A DIAMINE OR TRIAMINE AND A DICARBOXYLIC ACID OR ESTER IN THE PRESENCE OF A BASE AND SOLVENT; COUPLING AGENT; REDUCTION; COMPLEXING WITH MANGANESE COMPOUNDS; ION EXCHANGING | THE MONSANTO COMPANY (US) | 1998-02-24 | — | — | US | disclosed |