Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 7/20 | 0.51 |
| ▸ | IKBKB | O14920 | 4/20 | 0.51 |
| ▸ | RARB | P10826 | 5/20 | 0.46 |
| ▸ | RARG | P13631 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.42 |
| ▸ | GOT1 | P17174 | 1/20 | 0.42 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8692338 | 0.89 | RARA (0.45) | RARAIKBKBRARBRARGMEN1 | |
| SCHEMBL8691663 | 0.83 | RARA (0.58) | RARAIKBKBRARBRARGMEN1 | |
| SCHEMBL8690758 | 0.82 | RARA (0.65) | RARAIKBKBRARBRARGMEN1 | |
| SCHEMBL8426145 | 0.82 | RARA (0.63) | RARAIKBKBRARBRARGMEN1 | |
| SCHEMBL8396524 | 0.82 | RARA (0.38) | RARAIKBKBRARBRARGMEN1 | |
| SCHEMBL8691391 | 0.81 | RARA (0.54) | RARAIKBKBRARBRARGMEN1 | |
| SCHEMBL8428658 | 0.80 | RARA (0.55) | RARAIKBKBRARBRARGMEN1 | |
| SCHEMBL8695385 | 0.78 | RARA (0.45) | RARAIKBKBRARBRARGMEN1 | |
| SCHEMBL8839055 | 0.76 | RARA (0.56) | RARAIKBKBRARBRARGMEN1 | |
| SCHEMBL8690793 | 0.76 | RARA (0.61) | RARAIKBKBRARBRARGMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5786379-A | Adamantyl-substituted biaromatic compounds and pharmaceutical/cosmetic compositions comprised thereof | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1998-07-28 | — | — | US | disclosed |