Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 12/20 | 0.53 |
| ▸ | DPP8 | Q6V1X1 | 7/20 | 0.53 |
| ▸ | DPP9 | Q86TI2 | 7/20 | 0.53 |
| ▸ | DPP7 | Q9UHL4 | 7/20 | 0.53 |
| ▸ | FAP | Q12884 | 5/20 | 0.53 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | TACR1 | P25103 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8701022 | 0.81 | DPP4 (0.56) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL8698184 | 0.78 | DPP4 (0.54) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL24989201 | 0.74 | DPP4 (0.69) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL8699172 | 0.74 | DPP4 (0.56) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL14985801 | 0.73 | DPP4 (0.67) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL6162266 | 0.73 | DPP4 (0.73) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL14985790 | 0.73 | DPP4 (0.63) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL8696456 | 0.73 | DPP4 (0.54) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL9001325 | 0.72 | DPP4 (0.66) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL9001328 | 0.72 | DPP4 (0.66) | DPP4DPP8DPP9DPP7FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5741799-A | ANTICOAGULANTS OF SULFONAMIDO HETEROCYCLIC THROMBIN INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-04-21 | — | — | US | disclosed |
| US-5741792-A | ANTICOAGULANTS OF SULFONAMIDO HETEROCYCLIC THROMBIN INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-04-21 | — | — | US | disclosed |