SCHEMBL869685

SCHEMBL869685

C=C(O)C=Cc1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.58
HDAC3 O15379 2/20 0.58
HDAC4 P56524 2/20 0.58
HDAC1 Q13547 2/20 0.58
HDAC2 Q92769 2/20 0.58
HDAC8 Q9BY41 2/20 0.58
HDAC6 Q9UBN7 2/20 0.58
PLIN1 O60240 2/20 0.58
LMNA P02545 2/20 0.58
RECQL P46063 2/20 0.58
PLIN5 Q00G26 2/20 0.58
ABHD5 Q8WTS1 2/20 0.58
ALDH1A1 P00352 2/20 0.58
F3 P13726 2/20 0.58
TNKS O95271 1/20 0.58
HCAR2 Q8TDS4 1/20 0.58
HDAC7 Q8WUI4 1/20 0.58
HDAC10 Q969S8 1/20 0.58
HDAC11 Q96DB2 1/20 0.58
TNKS2 Q9H2K2 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12261578 1.00 MAPT (0.58) MAPTHDAC3HDAC4HDAC1HDAC2
SCHEMBL1999706 0.84 MAPT (0.58) MAPTHDAC3HDAC4HDAC1HDAC2
SCHEMBL1999708 0.84 MAPT (0.58) MAPTHDAC3HDAC4HDAC1HDAC2
SCHEMBL27640189 0.82 MAPT (0.56) MAPTHDAC3HDAC4HDAC1HDAC2
SCHEMBL12252392 0.82 MAPT (0.56) MAPTHDAC3HDAC4HDAC1HDAC2
SCHEMBL4856786 0.82 MAPT (0.56) MAPTHDAC3HDAC4HDAC1HDAC2
SCHEMBL13082341 0.81 MAOB (0.61) MAPTHDAC3HDAC4HDAC1HDAC2
SCHEMBL30688107 0.80
SCHEMBL16067308 0.80 TYR (0.61) MAPTHDAC6LMNAALDH1A1F3
SCHEMBL551222 0.80 MAPT (0.54) MAPTHDAC3HDAC4HDAC1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210223242-A1 METHOD FOR THE DETECTION OF APOLIPOPROTEIN E4 SPHINGOTEC GMBH (DE) 2021-07-22 US claimed
US-20210199646-A1 SAMPLE DEPLETION AND ENRICHMENT TO IMPROVE THE QUALITY OF DIAGNOSTIC TEST RESULTS VERAVAS, INC. 2021-07-01 US claimed
US-10948484-B2 Sample depletion and enrichment to improve the quality of diagnostic test results VERAVAS, INC. (US) 2021-03-16 US claimed
EP-3526605-A1 METHOD FOR THE DETECTION OF APOLIPOPROTEIN E4 sphingotec GmbH (DE) 2019-08-21 EP claimed
US-20190137484-A9 Sample depletion and enrichment to improve the quality of diagnostic test results VERAVAS, INC. (US) 2019-05-09 US claimed
US-20180292394-A1 Sample depletion and enrichment to improve the quality of diagnostic test results SOLDO JOSHUA CAINE (US) 2018-10-11 US claimed
WO-2018069437-A1 METHOD FOR THE DETECTION OF APOLIPOPROTEIN E4 SPHINGOTEC GMBH (DE) 2018-04-19 WO claimed
EP-3309550-A1 METHOD FOR THE DETECTION OF APOLIPOPROTEIN E4 sphingotec GmbH (DE) 2018-04-18 EP claimed
CN-115745718-B Preparation method of delta-hydroxy substituted aromatic acetonitrile derivative 浙江工业大学台州研究院 2024-02-13 CN disclosed
US-20230091170-A1 ENRICHMENT OF ANTIGEN-SPECIFIC ANTIBODIES FOR ANALYTIC AND THERAPEUTIC USE VERAVAS, INC. 2023-03-23 US disclosed
CN-115745718-A Preparation method of delta-hydroxy substituted aromatic acetonitrile derivative 浙江工业大学台州研究院 2023-03-07 CN disclosed
EP-4133271-A1 ENRICHMENT OF ANTIGEN-SPECIFIC ANTIBODIES FOR ANALYTIC AND THERAPEUTIC USE Veravas, Inc. (US) 2023-02-15 EP disclosed
US-20210302416-A1 METHOD FOR DETECTING BIOMARKERS VERAVAS, INC. 2021-09-30 US disclosed
US-20210223242-A1 METHOD FOR THE DETECTION OF APOLIPOPROTEIN E4 SPHINGOTEC GMBH (DE) 2021-07-22 US disclosed
US-20030142704-A1 Micro-lasing beads and structures for combinatorial chemistry and other applications, and techniques for fabricating the structures and for detecting information encoded by the structures LAWANDY NABIL M (US) 2003-07-31 US disclosed
US-20030142713-A1 Micro-lasing beads and structures for combinatorial chemistry and other applications, and techniques for fabricating the structures and for detecting information encoded by the structures LAWANDY NABIL M (US) 2003-07-31 US disclosed
EP-1252126-A1 NONREDUNDANT SPLIT/POOL SYNTHESIS OF COMBINATORIAL LIBRARIES Nanoscale Combinatorial Synthesis, Inc. (US) 2002-10-30 EP disclosed
US-20010041344-A1 Nonredundant split/pool synthesis of combinatorial libraries NANOSCALE COMBINATORIAL SYNTHESIS, INC., 625 CLYDE AVENUE, MOUNTAIN VIEW, CA 94043 2001-11-15 US disclosed
WO-2001056955-A1 NONREDUNDANT SPLIT/POOL SYNTHESIS OF COMBINATORIAL LIBRARIES NANOSCALE COMBINATORIAL SYNTHESIS, INC. (US) 2001-08-09 WO disclosed
EP-0681003-A2 Resin composition and a method of curing the same KANSAI PAINT CO., LTD. (JP) 1995-11-08 EP disclosed