Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 18/20 | 0.61 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.54 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8702210 | 0.91 | CYP19A1 (0.64) | CYP19A1CYP26A1CYP11B1 | |
| SCHEMBL8697578 | 0.88 | CYP19A1 (0.60) | CYP19A1CYP26A1CYP11B1 | |
| SCHEMBL8700795 | 0.88 | CYP19A1 (0.60) | CYP19A1CYP26A1CYP11B1 | |
| SCHEMBL8697114 | 0.84 | CYP19A1 (0.64) | CYP19A1CYP26A1CYP11B1 | |
| SCHEMBL11355223 | 0.83 | CYP19A1 (0.79) | CYP19A1CYP26A1CYP11B1 | |
| SCHEMBL11355092 | 0.80 | CYP19A1 (0.79) | CYP19A1CYP26A1CYP11B1 | |
| SCHEMBL8702846 | 0.79 | CYP19A1 (0.57) | CYP19A1 | |
| SCHEMBL8702653 | 0.78 | CYP19A1 (0.67) | CYP19A1CYP26A1CYP11B1 | |
| SCHEMBL8700535 | 0.75 | CYP19A1 (1.00) | CYP19A1CYP26A1 | |
| SCHEMBL8696297 | 0.75 | CYP19A1 (0.69) | CYP19A1CYP26A1CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998018791-A1 | HETEROCYCLIC FURAN COMPOUNDS, THEIR PREPARATION AND USE AS AROMATASE INHIBITORS | A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE S.R.L. (IT) | 1998-05-07 | — | — | WO | claimed |