Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 15/20 | 0.60 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.54 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8702210 | 0.91 | CYP19A1 (0.64) | CYP19A1CYP26A1PDE4BCYP3A4CYP2C19 | |
| SCHEMBL8697578 | 0.88 | CYP19A1 (0.60) | CYP19A1CYP26A1PDE4BCYP3A4CYP2C19 | |
| SCHEMBL8696928 | 0.88 | CYP19A1 (0.61) | CYP19A1CYP26A1CYP11B1 | |
| SCHEMBL8697114 | 0.84 | CYP19A1 (0.64) | CYP19A1CYP26A1CYP3A4CYP2C19CYP1A2 | |
| SCHEMBL8699139 | 0.79 | CYP19A1 (0.38) | CYP19A1PDE4BCYP3A4CYP11B1CYP11B2 | |
| SCHEMBL9368105 | 0.78 | CYP19A1 (0.68) | CYP19A1CYP26A1CYP3A4CYP2C19CYP11B1 | |
| SCHEMBL8697621 | 0.78 | CYP19A1 (0.61) | CYP19A1CYP26A1CYP3A4CYP11B1CYP11B2 | |
| SCHEMBL8697507 | 0.75 | CYP19A1 (1.00) | CYP19A1CYP26A1CYP3A4CYP2C19CYP1A2 | |
| SCHEMBL8697937 | 0.75 | CYP19A1 (0.60) | CYP19A1CYP26A1CYP3A4CYP2C19CYP1A2 | |
| SCHEMBL11367077 | 0.75 | CYP19A1 (0.79) | CYP19A1CYP26A1CYP3A4CYP2C19CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998018791-A1 | HETEROCYCLIC FURAN COMPOUNDS, THEIR PREPARATION AND USE AS AROMATASE INHIBITORS | A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE S.R.L. (IT) | 1998-05-07 | — | — | WO | claimed |