N-Benzylaniline

N-Benzylaniline

SCHEMBL8697172

ClCc1ccccc1.c1ccc(CNc2ccccc2)cc1

nearest known ligand 0.78

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.59
CYP1A2 P05177 2/20 0.53
MEN1 O00255 1/20 0.53
CYP3A4 P08684 1/20 0.53
CYP2C9 P11712 1/20 0.53
CYP2C19 P33261 1/20 0.53
KMT2A Q03164 1/20 0.53
LTA4H P09960 1/20 0.53
FFAR1 O14842 2/20 0.50
PTPN1 P18031 2/20 0.50
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
CA12 O43570 1/20 0.50
CA9 Q16790 1/20 0.50
ALDH1A1 P00352 1/20 0.50
CYP2D6 P10635 1/20 0.50
PTPRF P10586 1/20 0.50
PTPN2 P17706 1/20 0.50
PTPN11 Q06124 1/20 0.50
FFAR4 Q5NUL3 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14804150 0.94 HTT (0.62) HTTCYP1A2MEN1CYP3A4CYP2C9
SCHEMBL22628164 0.89 HTT (0.71) HTTCYP1A2MEN1CYP3A4CYP2C9
N-Benzylaniline SCHEMBL7840 0.89 HTT (0.71) HTTCYP1A2MEN1CYP3A4CYP2C9
N-Benzylaniline SCHEMBL2176624 0.86 HTT (0.68) HTTCYP1A2MEN1CYP3A4CYP2C9
N-Benzylaniline SCHEMBL357137 0.86 HTT (0.68) HTTCYP1A2MEN1CYP3A4CYP2C9
N-Benzylaniline SCHEMBL27620362 0.86 HTT (0.68) HTTCYP1A2MEN1CYP3A4CYP2C9
N-Benzylaniline SCHEMBL3602124 0.86 HTT (0.68) HTTCYP1A2MEN1CYP3A4CYP2C9
N-Benzylaniline SCHEMBL10963734 0.84 HTT (0.65) HTTCYP1A2MEN1CYP3A4CYP2C9
SCHEMBL2065031 0.84 CYP1A2 (0.69) HTTCYP1A2MEN1CYP3A4CYP2C9
SCHEMBL1924100 0.84 HTT (0.78) HTTCYP1A2MEN1CYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5767290-A PROTECTION OF AMINE BY A TOCOPHERYL RADICAL; MILD CONDITIONS FOR DEPROTECTING; SYNTHESIS OF OLIGOPEPTIDES BASF AKTIENGESELLSCHAFT (DE) 1998-06-16 US disclosed