Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 4/20 | 0.48 |
| ▸ | MGAM | O43451 | 1/20 | 0.48 |
| ▸ | SI | P14410 | 1/20 | 0.48 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | PPID | Q08752 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7873229 | 0.86 | GAA (0.48) | SMN1; SMN2ALDH1A1GAAMGAMSI | |
| SCHEMBL8394622 | 0.83 | SMN1; SMN2 (0.58) | SMN1; SMN2ALDH1A1GAAMGAMSI | |
| SCHEMBL124577 | 0.81 | KMT2A (0.59) | SMN1; SMN2ALDH1A1GAAMGAMSI | |
| SCHEMBL28897222 | 0.81 | KMT2A (0.59) | SMN1; SMN2ALDH1A1GAAKMT2AMAPT | |
| SCHEMBL17433663 | 0.80 | KMT2A (0.57) | SMN1; SMN2ALDH1A1GAAMGAMSI | |
| SCHEMBL31439645 | 0.80 | KMT2A (0.57) | SMN1; SMN2ALDH1A1GAAMGAMSI | |
| SCHEMBL28792148 | 0.80 | KMT2A (0.57) | SMN1; SMN2ALDH1A1GAAMGAMSI | |
| SCHEMBL17433641 | 0.80 | KMT2A (0.57) | SMN1; SMN2ALDH1A1GAAMGAMSI | |
| SCHEMBL17433560 | 0.80 | KMT2A (0.57) | SMN1; SMN2ALDH1A1GAAMGAMSI | |
| SCHEMBL6753757 | 0.80 | KMT2A (0.57) | SMN1; SMN2ALDH1A1GAAMGAMSI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852028-A | Pyrimidine carboxylates and related compounds and methods for treating inflammatory conditions | SIGNAL PHARMACEUTICALS, INC. (US) | 1998-12-22 | — | — | US | disclosed |