Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5202983 | 0.81 | PIK3CD (0.47) | ALDH1A1POLBMEN1KMT2AHPGD | |
| SCHEMBL17507358 | 0.78 | PSIP1 (0.42) | ALDH1A1POLBMEN1KMT2AHPGD | |
| SCHEMBL3877161 | 0.78 | GAA (0.44) | ALDH1A1POLBMEN1KMT2ATSHR | |
| SCHEMBL11572085 | 0.77 | HSD17B10 (0.52) | ALDH1A1POLBMEN1KMT2AHPGD | |
| SCHEMBL17526252 | 0.77 | MCL1 (0.42) | ALDH1A1POLBMEN1KMT2AHPGD | |
| SCHEMBL7109004 | 0.76 | HTT (0.56) | ALDH1A1POLBHPGDTSHRMAPT | |
| SCHEMBL8696573 | 0.75 | MCL1 (0.51) | ALDH1A1POLBMEN1KMT2ACYP3A4 | |
| SCHEMBL114903 | 0.74 | PIK3CA (0.52) | ALDH1A1PIK3CA | |
| SCHEMBL19221593 | 0.73 | MAPT (0.46) | ALDH1A1POLBMEN1KMT2AHPGD | |
| SCHEMBL17526214 | 0.73 | CYP3A4 (0.40) | ALDH1A1POLBMEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998028280-A1 | CERTAIN 3-[2,4-DISUBSTITUTED-5-(SUBSTITUTED AMINO)PHENYL]-1-SUBSTITUTED-6-TRIFLUOROMETHYL-2,4-(1H,3H)-PYRIMIDINEDIONE DERIVATIVES AS HERBICIDES | FMC CORPORATION (US) | 1998-07-02 | — | — | WO | disclosed |